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Related Concept Videos

Sinusoidal Sources01:18

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Graphical and Analytic Representation of Sinusoids01:20

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Analyzing two sinusoidal voltages with equal amplitude and period but different phases on an oscilloscope, an instrument used to display and analyze waveforms, involves a three-step process.
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Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment01:08

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Hepatic impairment, characterized by decreased liver function, does not uniformly mandate adjustments in drug dosage. Whether dosage modifications are necessary depends on various factors related to the drug's metabolism and elimination pathways. If a drug is primarily excreted via the kidneys and bypasses significant hepatic processing, if it undergoes minimal metabolic transformation in the liver, or if it is volatile and primarily expelled through the lungs, dose adjustments may not be...
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The hepatic portal system, a critical part of our circulatory framework, transports nutrient-laden, deoxygenated blood from the gastrointestinal tract and spleen to the liver. This ingenious system plays an indispensable role in maintaining our body's metabolic equilibrium.
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Related Experiment Video

Updated: Feb 15, 2026

A Flow Adhesion Assay to Study Leucocyte Recruitment to Human Hepatic Sinusoidal Endothelium Under Conditions of Shear Stress
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Hepatic sinusoidal dilatation.

Giuseppe Brancatelli1, Alessandro Furlan2, Alberto Calandra3

  • 1Section of Radiological Sciences, Department of Biopathology and Medical Biotechnologies, Di.Bi. Med, University of Palermo, Via del Vespro 129, 90127, Palermo, Italy. gbranca@yahoo.com.

Abdominal Radiology (New York)
|February 3, 2018
PubMed
Summary
This summary is machine-generated.

Hepatic sinusoidal dilatation, an enlargement of liver capillaries, often stems from venous outflow obstruction. However, it can also occur with extrahepatic inflammation, impacting liver parenchyma.

Keywords:
Hepatic veinsLiverMosaic patternSinusoid

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Isolation and Characterization of Mouse Primary Liver Sinusoidal Endothelial Cells
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Area of Science:

  • Radiology
  • Hepatology
  • Vascular Medicine

Background:

  • Hepatic sinusoidal dilatation involves enlarged hepatic capillaries.
  • It is frequently caused by hepatic venous outflow obstruction, leading to vascular stasis and hepatic parenchyma congestion.
  • Causes include pericardial disease, heart failure, hepatic vein or inferior vena cava compression/thrombosis (Budd-Chiari syndrome), and sinusoidal obstruction syndrome.

Purpose of the Study:

  • To describe the imaging characteristics of hepatic sinusoidal dilatation.
  • To differentiate causes of hepatic sinusoidal dilatation based on imaging findings.
  • To explore associations between hepatic sinusoidal dilatation and both intrahepatic and extrahepatic conditions.

Main Methods:

  • Review of contrast-enhanced cross-sectional imaging studies.
  • Analysis of hepatic and extrahepatic imaging features.
  • Correlation of imaging findings with clinical conditions.

Main Results:

  • Hepatic sinusoidal dilatation typically presents as a mottled, reticular "mosaic" liver enhancement pattern on contrast-enhanced imaging.
  • Dilated hepatic veins and ascites are additional imaging indicators.
  • Extrahepatic inflammatory conditions can cause hepatic sinusoidal dilatation without venous outflow obstruction.

Conclusions:

  • Hepatic sinusoidal dilatation has characteristic imaging features on cross-sectional studies.
  • Imaging findings, including the "mosaic" pattern and associated features, aid in diagnosing the cause.
  • Understanding these patterns is crucial for differentiating between venous outflow obstruction and inflammatory causes.