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Acupuncture for patients with chronic functional constipation: A randomized controlled trial.

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Acupuncture effectively manages chronic functional constipation (CFC), showing sustained improvements in bowel movements compared to mosapride. This study highlights acupuncture as a viable treatment option for CFC.

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Area of Science:

  • Gastroenterology
  • Integrative Medicine
  • Clinical Research

Background:

  • Chronic functional constipation (CFC) poses a significant health challenge.
  • Acupuncture is a traditional Chinese medicine treatment for CFC with limited clinical evidence.
  • This study investigates the efficacy and safety of acupuncture for CFC management.

Purpose of the Study:

  • To evaluate the effectiveness of three acupuncture techniques (He, Shu-mu, He-shu-mu) compared to mosapride for CFC.
  • To assess changes in spontaneous bowel movements (SBMs) and stool consistency.
  • To monitor adverse events associated with acupuncture treatment.

Main Methods:

  • A multicenter randomized controlled trial involving 684 patients with CFC.
  • Patients were randomized into four groups: He acupuncture, Shu-mu acupuncture, He-shu-mu acupuncture, or oral mosapride.
  • Treatment involved 16 sessions over 4 weeks, with outcomes assessed at weeks 4 and 8.

Main Results:

  • All four groups showed increased SBMs at week 4, with no significant difference between groups.
  • At week 8, acupuncture groups demonstrated significantly greater increases in SBMs compared to the mosapride group (P=.005).
  • Secondary outcomes like stool consistency also improved, with acupuncture showing comparable or superior results.

Conclusions:

  • Acupuncture treatments (He, Shu-mu, He-shu-mu) are effective in improving stool frequency and consistency in patients with CFC.
  • Acupuncture demonstrated comparable short-term efficacy to mosapride and superior long-term effects on SBMs.
  • Further research, including sham-controlled trials, is needed to fully elucidate the magnitude of acupuncture's treatment effect.