Related Experiment Video
Updated: Feb 15, 2026

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
Published on: November 5, 2019
Challenges and opportunities for meningococcal vaccination in the developing world
Rouba Shaker1, Danielle Fayad1, Ghassan Dbaibo1,2
1a Department of Pediatrics and Adolescent Medicine, Division of Pediatric Infectious Diseases, and Center for Infectious Diseases Research , American University of Beirut Medical Center , Beirut , Lebanon.
Implementing meningococcal vaccination in developing countries faces challenges like poor data and funding. Solutions include better surveillance, financial aid, and affordable vaccine development for disease control.
Area of Science:
- Epidemiology
- Vaccinology
- Global Health
Background:
- Meningococcal disease remains a severe infection with significant mortality and morbidity, even with treatment.
- Meningococcal vaccines are crucial for disease control, but their implementation faces substantial obstacles, particularly in developing nations.
Purpose of the Study:
- To identify challenges hindering meningococcal vaccine use in developing countries.
- To explore opportunities and solutions for improving meningococcal immunization programs in these regions.
Main Methods:
- This study is a review identifying challenges and solutions.
- It synthesizes information on epidemiologic, financial, and logistical barriers.
Main Results:
- Key challenges include inadequate epidemiologic data for targeted vaccination and significant financial constraints.
- Successful implementation requires enhanced surveillance, financial aid, and collaborative development of affordable vaccines.
Conclusions:
- Overcoming barriers to meningococcal vaccination in developing countries necessitates a multi-faceted approach.
- Strategies must include improved data collection, sustained financial support, and partnerships for cost-effective vaccine development and deployment.
Related Concept Videos
Vaccinations
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Sustainable Development
Language Development
The critical period for language acquisition suggests that the ability to acquire language is at its peak early in life. As people age, this proficiency decreases. Language development begins very...
Development of the Lymphatic System
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...

