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Published on: July 1, 2020
Similarities and Differences between Silver Ions and Silver in Nanoforms as Antibacterial Agents
Anna Kędziora1, Mateusz Speruda2, Eva Krzyżewska3
1Department of Microbiology, Institute of Genetics and Microbiology, University of Wrocław, 51-148 Wrocław, Poland. anna.kedziora@uwr.edu.pl.
Abstract:
Silver is considered as antibacterial agent with well-known mode of action and bacterial resistance against it is well described. The development of nanotechnology provided different methods for the modification of the chemical and physical structure of silver, which may increase its antibacterial potential. The physico-chemical properties of silver nanoparticles and their interaction with living cells differs substantially from those of silver ions. Moreover, the variety of the forms and characteristics of various silver nanoparticles are also responsible for differences in their antibacterial mode of action and probably bacterial mechanism of resistance. The paper discusses in details the aforementioned aspects of silver activity.
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