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Integration of Antibody Array Technology into Drug Discovery and Development
Wei Huang1, Kelly Whittaker2, Huihua Zhang1
11 Raybiotech, Inc. , Guangzhou, China .
Assay and Drug Development Technologies
|February 3, 2018
Summary
Antibody arrays offer high-throughput protein detection for biomarker discovery and drug development. This technology is crucial for advancing drug discovery by analyzing protein profiles in various stages.
Area of Science:
- Biotechnology
- Proteomics
- Drug Discovery
Background:
- Antibody arrays are high-throughput tools for parallel protein detection.
- They are increasingly used for biomarker identification and in drug discovery research.
Purpose of the Study:
- To review antibody array technologies and their applications in drug discovery.
- To discuss the relevance of antibody arrays in various stages of the drug discovery process.
Main Methods:
- Review of recent literature on antibody array technologies.
- Discussion of technical aspects and available platforms for antibody arrays.
Main Results:
- Antibody arrays are valuable for identifying disease biomarkers.
- They are applied in target identification, understanding drug resistance, and drug action mechanisms.
- Applications extend to clinical trials and patient care management.
Conclusions:
- Antibody array technology is a powerful tool for protein profiling in drug discovery.
- Its ability to analyze protein events makes it vital for understanding disease and developing therapeutics.
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