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Distribution of Anterior Chamber Parameters in Normal Chinese Children and the Associated Factors

Jing Wang1,2,3, Xiangui He1,4, Shuyu Xiong1,2,3

  • 1Department of Eye Disease Prevention and Treatment, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital.

Journal of Glaucoma
|February 3, 2018
PubMed

Insights

This study describes anterior eye chamber parameters in Shanghai children, finding that anterior chamber volume and depth correlate with age, while the anterior chamber angle remains stable. These findings enhance understanding of pediatric ocular development.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Biometry

Background:

  • Understanding the normal distribution of anterior chamber parameters is crucial for diagnosing various ocular conditions in children.
  • Factors influencing anterior chamber dimensions in pediatric populations require further investigation.

Purpose of the Study:

  • To determine the distribution of anterior chamber depth (ACD), anterior chamber volume (ACV), and anterior chamber angle (ACA) in a pediatric population in Shanghai, China.
  • To identify factors associated with variations in these anterior segment parameters.

Main Methods:

  • A cross-sectional study involving 1321 children aged 6 to 18 years from Shanghai schools.
  • Anterior eye chamber parameters (ACD, ACV, ACA) were measured using a Pentacam Scheimpflug camera.
  • Statistical analysis was performed to assess associations with age, sex, BMI, refractive error, axial length, and intraocular pressure.

Main Results:

  • Mean ACA, ACD, and ACV were 37.95±7.96 degrees, 3.22±0.23 mm, and 194.89±28.95 mm³, respectively.
  • Boys exhibited higher ACA, ACD, and ACV compared to girls.
  • ACV and ACD showed similar age-related growth trends, while ACA remained stable; 5% of children had ACA ≤24.91 degrees.
  • Wider ACA was independently associated with greater ACV, deeper ACD, shorter pupil diameter, shorter axial length, and thinner central corneal thickness.

Conclusions:

  • Anterior chamber angle (ACA) is a stable parameter with age, serving as a key indicator for angle closure.
  • This study provides valuable data on the distribution of anterior chamber parameters in Chinese children.
  • The findings contribute to a better understanding of factors influencing anterior segment variations in pediatric eyes.
Abstract

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