[A Case of Duodenal Cancer with Familial Adenomatous Polyposis]

A 34-year-old man was diagnosed with familial adenomatous polyposis(FAP)in September 2011, and he underwent endoscopic mucosal resection(EMR)due to multiple polyps in the duodenum and small intestine. Three months later, duodenal cancer was found, and he underwent a subsequent EMR. The pathological findings showed residual cancer cells in the lateral margin; therefore, EMR was performed again. Total colectomy and partial resection of the small intestine was performed in December 2012. Esophagogastroduodenoscopy(EGD)was then performed every 3-6 months, and EMR was performed 4 times. We followed up the patient annually, starting 2014. In January 2016, recurrence of the duodenal cancer was found; therefore, he underwent a pancreatoduodenectomy. The pathological diagnosis was adenocarcinoma, tub2> tub1, pT1a, N0, M0, fStage I A. There were many adenomas ranging from low-grade to high-grade in the duodenal mucosa. The patient remains well without any evidence of cancer recurrence more than 18 months after the last operation. When treating patients with duodenal adenoma complicated by FAP, regardless of age, strict follow-up is important.