[Possible inducible nature of radioresistant DNA synthesis stimulated by 5-fluorodeoxyuridine]

A study was made of the effect of cycloheximide on the radioresistant DNA synthesis stimulated by preincubation of cells with 5-fluorodeoxyuridine (FdUrd). It was shown that after the cycloheximide treatment the radioresistant DNA synthesis was absent while in FdUrd-treated cells it did occur. It is assumed that the FdUrd-stimulated radioresistant DNA synthesis is of an inducible nature.