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An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions
Published on: June 30, 2021
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Therapeutic Opportunities in Intestinal Microbiota-Virus Interactions
Vicente Monedero1, María Carmen Collado1, Jesús Rodríguez-Díaz2
1Lactic Acid Bacteria and Probiotics Laboratory, Institute of Agrochemistry and Food Technology (IATA-CSIC), Paterna, Spain.
Trends in Biotechnology
|February 4, 2018
Summary
The gut microbiota influences viral infections. Modulating gut microbes offers new ways to prevent and treat viral gut infections.
Area of Science:
- Microbiology
- Virology
- Immunology
Background:
- The host microbiota plays a crucial role in health and disease.
- Interactions between hosts, pathogens, and the microbiota are complex.
- Viral enteric infections pose significant health challenges.
Purpose of the Study:
- To explore the role of the host microbiota in viral pathogen interactions.
- To investigate the potential of microbial modulation for managing viral enteric infections.
Main Methods:
- Review of current literature on host-microbiota-virus interactions.
- Analysis of studies investigating microbial modulation strategies.
Main Results:
- The gut microbiota is increasingly recognized as a key factor in host-pathogen dynamics.
- Modulating the intestinal microbial composition presents a promising therapeutic avenue.
Conclusions:
- Targeting the host microbiota offers novel strategies for preventing and treating viral enteric infections.
- Further research into microbial modulation can lead to innovative treatments for viral diseases.
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