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Updated: Feb 15, 2026

Whole-animal Imaging and Flow Cytometric Techniques for Analysis of Antigen-specific CD8+ T Cell Responses after Nanoparticle Vaccination
Published on: April 29, 2015
Heavy Water Shedding Light on Antigen-Specific T Cell Responses
1Dermatology and Venereology Unit, Department of Medicine Solna, Karolinska Institutet, 171 76 Stockholm, Sweden; Department of Dermatology, Karolinska University Hospital Solna, 171 76 Stockholm, Sweden.
Abstract:
CD8 T cells are crucial for long-term immunity. Nevertheless, the in vivo differentiation of human naïve CD8 T cells into effector and memory populations remains ill-defined. A recent study assesses the in vivo turnover of human antigen-specific CD8 T cells and suggests that long-lived memory cells arise from effector cells.
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