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Prenatal diagnosis of funisitis: two case reports
Daisuke Katsura1, Yuichiro Takahashi2, Shigenori Iwagaki2
1Department of Fetal-Maternal Medicine, Nagara Medical Center, 1300-7 Nagara, Gifu, 502-8558, Japan. katsuo14@belle.shiga-med.ac.jp.
This study reports the first prenatal diagnosis of acute funisitis using ultrasonography. Characteristic ultrasound findings can help identify this fetal inflammation, aiding in early diagnosis and management.
Area of Science:
- Perinatology
- Fetal Medicine
- Diagnostic Imaging
Background:
- Acute funisitis, a fetal inflammatory condition, involves neutrophil infiltration into Wharton's jelly.
- Prenatal diagnosis of acute funisitis via ultrasonography has not been previously documented.
Observation:
- Two cases presented with oligohydramnios and threatened premature delivery at 26-27 weeks gestation.
- Ultrasonography revealed non-uniform Wharton's jelly thickening, heterogeneous internal echoes, and hyper-echoid umbilical vessel walls.
Findings:
- Prenatal diagnosis of acute funisitis was made based on characteristic ultrasonographic findings.
- Postpartum histopathology confirmed severe funisitis in both cases.
Implications:
- This marks the first reported instance of prenatal ultrasonographic diagnosis of funisitis.
- Ultrasonographic findings suggestive of intrauterine infection warrant consideration of severe funisitis in the differential diagnosis.
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