Related Experiment Video
Updated: Feb 15, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
Limbic Encephalitis Manifesting as Selective Amnesia and Seizure-like Activity: A Case Report
So-Yeon Kim1, Yoo Hyun Um1, Sung Chul Lim2
1Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract:
Limbic encephalitis (LE) is characterized by short-term memory loss, disorientation, agitation, seizures, and histopathological evidence of medial temporal lobe inflammation. Leucine-rich, glioma inactivated 1 (LGI-1) is an auto-antigen associated with LE. We report a 37-year-old male patient with LGI-1-related LE who presented with recurrent episodes of selective amnesia, seizure-like activity, confusion, and personality change. His symptoms were significantly improved with steroid therapy. Thorough differential diagnosis with consideration for autoimmune encephalitis should be in patients with presentation of symptoms, such as memory impairment, personality change and seizure-like activity, especially when other neurological diagnoses are excluded.
Related Concept Videos
Amnesia
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...
Dissociative Amnesia
T Cell Activation and Clonal Selection
Naive T cells that have not yet encountered an antigen express two primary CD...
Functional Brain Systems: Limbic System
Seizures: Classification
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Data Reporting and Recording

