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Associations Between Unplanned Cardiac Reinterventions and Outcomes After Pediatric Cardiac Operations
John M Costello1, Michael C Mongé2, Kevin D Hill3
1Division of Pediatric Cardiology, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Insights
Unplanned cardiac reinterventions after pediatric heart surgery occur in 5.4% of patients, especially neonates. These reinterventions increase operative mortality and hospital stay, highlighting the need for risk identification.
Area of Science:
- Pediatric Cardiac Surgery
- Congenital Heart Disease
- Healthcare Quality Improvement
Background:
- Pediatric heart operations carry risks of complications requiring further intervention.
- Understanding the incidence and predictors of unplanned cardiac reinterventions is crucial for improving patient outcomes.
- Previous studies have not comprehensively assessed risk factors and outcomes associated with these reinterventions.
Purpose of the Study:
- To determine the incidence of unplanned cardiac reinterventions in pediatric heart surgery patients.
- To identify risk factors associated with unplanned cardiac reinterventions.
- To explore the impact of reinterventions on operative mortality and postoperative length of stay (PLOS).
Main Methods:
- Analysis of The Society of Thoracic Surgeons Congenital Heart Surgery Database (January 2010 to June 2015).
- Inclusion of patients aged 18 years or younger undergoing cardiac operations.
- Multivariable regression used to assess risk factors for reintervention and its association with outcomes.
Main Results:
- Unplanned cardiac reinterventions occurred in 5.4% of 84,404 patients, with higher rates in neonates (11.8%).
- Independent risk factors included noncardiac anomalies, younger age, lower weight, prior operations, and preoperative ventilation.
- Reintervention was a significant risk factor for operative mortality (aOR 5.3) and longer PLOS (aRR 2.3).
Conclusions:
- Unplanned cardiac reinterventions are common, particularly in neonates, and significantly increase operative mortality and PLOS.
- Preoperative identification of high-risk patients can facilitate targeted quality improvement initiatives.
- These findings underscore the importance of optimizing perioperative care to minimize reinterventions.
Background:
After pediatric heart operations, we sought to determine the incidence of unplanned cardiac reinterventions during the same hospitalization, assess risk factors for these reinterventions, and explore associations between reinterventions and outcomes. We hypothesized that younger patients undergoing more complex operations would be at greater risk for unplanned cardiac reinterventions and that operative mortality and postoperative length of stay (PLOS) would be greater in patients who undergo reintervention than in those who do not.
Methods:
Patients aged 18 years or younger in The Society of Thoracic Surgeons Congenital Heart Surgery Database (January 2010 to June 2015) were included. We used multivariable regression to evaluate risk factors for unplanned cardiac reintervention (operation or therapeutic catheterization) and associations of reintervention with operative mortality and PLOS.
Results:
Of 84,404 patients (117 centers), 21% were neonates and 36% infants. An unplanned cardiac reintervention was performed in 5.4% of patients, including 11.8% of neonates, 5.2% of infants, and 2.8% of children. Independent risk factors for unplanned reintervention included presence of noncardiac anomalies/genetic syndromes, nonwhite race, younger age, lower weight among neonates and infants, prior cardiothoracic operations, preoperative mechanical ventilation, other Society of Thoracic Surgeons preoperative risk factors, and higher Society of Thoracic Surgeons-European Association for Cardiothoracic Surgery Mortality Category (adjusted p < 0.001 for all). Unplanned reintervention was a risk factor for operative mortality (adjusted odds ratio, 5.3; 95% confidence interval, 4.8 to 5.8; p < 0.001) and longer PLOS (adjusted relative risk, 2.3; 95% confidence interval, 2.2 to 2.4; p < 0.001).
Conclusions:
Unplanned cardiac reinterventions are not rare, particularly in neonates, and are independently associated with operative mortality and increased PLOS. Patients at greater risk may be identified preoperatively, presenting opportunities for quality improvement.
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