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Prevalence of Pediatric Functional Gastrointestinal Disorders Utilizing the Rome IV Criteria
Samantha G Robin1, Catherine Keller1, Russell Zwiener2
1Department of Medicine, Division of Gastroenterology and Hepatology, Center for Functional GI and Motility Disorders, University of North Carolina, Chapel Hill, NC.
Insights
Functional gastrointestinal (GI) disorders are common in children, affecting nearly 25% of both infants and older children. These conditions significantly impact quality of life and may be linked to parental GI health.
Area of Science:
- Pediatric Gastroenterology
- Epidemiology
- Public Health
Background:
- Functional gastrointestinal (GI) disorders are prevalent in children, impacting their well-being.
- The Rome IV criteria provide updated diagnostic guidelines for these conditions.
- Understanding the prevalence and impact of pediatric GI disorders is crucial for effective management.
Purpose of the Study:
- To determine the prevalence of functional GI disorders in children aged 0-18 years using the Rome IV criteria.
- To assess the impact of these disorders on children's quality of life (QoL).
- To explore potential associations between parental and child functional GI disorders.
Main Methods:
- A cross-sectional study involving 1255 mothers of children aged 0-18 years in the US.
- Online surveys were used to collect data on children's GI symptoms, QoL, and other health conditions.
- Diagnosis of functional GI disorders was based on the Rome IV criteria.
Main Results:
- Functional GI disorders were diagnosed in 24.7% of infants/toddlers (0-3 years) and 25.0% of children/adolescents (4-18 years).
- Infant regurgitation and functional constipation were the most common diagnoses.
- Children with functional GI disorders experienced significantly lower QoL compared to those without.
Conclusions:
- Functional GI disorders are common across all pediatric age groups based on Rome IV criteria.
- These disorders are associated with a significant reduction in pediatric quality of life.
- A higher likelihood of functional GI disorders in children was observed when parents also had these conditions.
Objective:
To assess the prevalence of functional gastrointestinal (GI) disorders in children 0-18 years old according to the newly established Rome IV diagnostic criteria as reported by parents in a representative community sample.
Study Design:
A cross-sectional study in which mothers (n = 1255) of children aged 0-18 years old in the US were recruited to complete an online survey about their child's GI symptoms, quality of life (QoL), and other health conditions.
Results:
Based on the Rome IV criteria, 24.7% of infants and toddlers aged 0-3 years and 25.0% of children and adolescents aged 4-18 years fulfilled symptom-based criteria for a functional GI disorder. The most common functional GI disorders were infant regurgitation among infants (24.1%) and functional constipation among both toddlers (18.5%) and children and adolescents (14.1%). QoL was diminished in pediatric patients with functional GI disorders (median = 71.69 vs median = 87.60; z = -11.41; P < .001). Children were more likely to qualify for a functional GI disorder if their parent qualified for a functional GI disorder (35.4% vs 23.0%; P < .001).
Conclusions:
Based on Rome IV criteria, functional GI disorders are common in pediatric populations of all ages and are associated with decreased QoL.
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