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Updated: Feb 15, 2026
08:34
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
21.2K
The evolution of proton beam therapy: Current and future status
Xiufang Tian1, Kun Liu1, Yong Hou1
1Department of Radiation Oncology, Qianfoshan Hospital Affiliated to Shandong University, Jinan, Shandong 250014, P.R. China.
Molecular and Clinical Oncology
|February 6, 2018
Summary
Proton beam therapy (PBT) offers improved cancer treatment by targeting tumors precisely, potentially enhancing survival and reducing side effects. However, high costs and ongoing research into its efficacy and biological effects present future challenges.
Area of Science:
- Oncology
- Radiation Physics
- Medical Technology
Background:
- Proton beam therapy (PBT) utilizes superior physical and dosimetric properties for cancer treatment.
- PBT aims to improve local tumor control and minimize normal tissue toxicity, potentially reducing adverse effects and enhancing patient survival.
Purpose of the Study:
- To provide an overview of current literature on the efficacy and toxicity of PBT in common oncological applications.
- To discuss the advantages, challenges, and future directions of PBT in cancer treatment.
Main Methods:
- Literature review of existing studies on proton beam therapy.
- Analysis of data regarding oncological applications, efficacy, and toxicity.
Main Results:
- PBT demonstrates potential for improved tumor treatment rates and reduced normal organ damage.
- Significant challenges include high facility costs, lack of extensive clinical trials, and immature imaging guidance.
Conclusions:
- PBT shows promise in oncology but faces economic and technical hurdles.
- Further research into clinical trials, biological effects, and imaging is crucial for PBT advancement.
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