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Related Concept Videos

Antisocial Personality Disorder01:24

Antisocial Personality Disorder

818
Antisocial personality disorder is a chronic mental health condition characterized by persistent patterns of disregard for the rights and well-being of others. Individuals with antisocial personality disorder exhibit behaviors that include deceitfulness, impulsivity, irresponsibility, aggression, and a profound lack of empathy. These traits often manifest early in life and persist into adulthood, leading to significant personal, social, and legal consequences.
Behavioral Characteristics and...
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Borderline Personality Disorder01:25

Borderline Personality Disorder

663
Borderline Personality Disorder is a complex and multifaceted mental health condition characterized by pervasive instability in interpersonal relationships, self-image, emotions, and impulse control. This instability manifests in extreme emotional reactions, fear of abandonment, and self-destructive behaviors. The disorder significantly impacts daily functioning, often leading to distress in both personal and professional domains.
Genetic and Environmental Contributions
Borderline Personality...
663
Personality Disorders: Paranoid and Schizoid01:22

Personality Disorders: Paranoid and Schizoid

706
Personality disorders represent enduring cognition, affect, and behavior patterns that significantly deviate from societal norms. These maladaptive traits often lead to difficulties in various domains, including interpersonal relationships, occupational settings, and overall psychological well-being. Paranoid personality disorder and schizoid personality disorder are two distinct conditions marked by odd or eccentric behavior.
Paranoid Personality Disorder
Paranoid personality disorder is...
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Personality Disorders: Schizotypal and Histrionic01:20

Personality Disorders: Schizotypal and Histrionic

626
Schizotypal personality disorder and histrionic personality disorder are two distinct psychological conditions classified under personality disorders, each characterized by unique behavioral patterns and social difficulties. Both disorders significantly affect interpersonal relationships and emotional well-being, leading to social isolation and frustration.
Schizotypal Personality Disorder: Eccentric Behavior and Social Withdrawal
Schizotypal personality disorder is marked by odd or eccentric...
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Personality Disorders: Narcissistic and Avoidant01:26

Personality Disorders: Narcissistic and Avoidant

859
Narcissistic and avoidant personality traits represent two contrasting patterns of behavior that significantly influence social interactions and self-perception. While individuals with narcissistic disorder seek admiration and validation, individuals with avoidant personality disorder withdraw due to fear of judgment.
Characteristics of Narcissistic Personality Disorder
Narcissistic individuals exhibit an inflated sense of self-importance and an excessive need for admiration. They are often...
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Personality Disorders: Dependent and Obsessive-Compulsive01:24

Personality Disorders: Dependent and Obsessive-Compulsive

468
Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
 Dependent Personality Disorder
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Related Experiment Video

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Immunohistochemical Visualization of Hippocampal Neuron Activity After Spatial Learning in a Mouse Model of Neurodevelopmental Disorders
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Antisocial Personality as a Neurodevelopmental Disorder.

Adrian Raine1

  • 1Departments of Criminology, Psychiatry, and Psychology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA;

Annual Review of Clinical Psychology
|February 6, 2018
PubMed
Summary

Antisocial personality disorder (APD) may be a neurodevelopmental disorder, suggesting early interventions could improve treatment. Research reviews brain imaging, genetics, and risk factors to support this neurodevelopmental view.

Keywords:
conduct disorderepigeneticsimagingneurocognitionpreventionpsychopathy

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Developmental Psychology

Background:

  • Antisocial personality disorder (APD) shows limited treatment progress.
  • Viewing APD as neurodevelopmental may enable early interventions.

Purpose of the Study:

  • To evaluate APD against neurodevelopmental disorder criteria.
  • To explore early intervention and prevention strategies for APD.

Main Methods:

  • Review of structural and functional brain imaging studies.
  • Analysis of neurocognition, genetics, epigenetics, and neurochemistry.
  • Examination of early health risk factors for APD.

Main Results:

  • Evidence suggests APD aligns with neurodevelopmental disorder characteristics.
  • Early onset conduct disorder may also have neurodevelopmental origins.

Conclusions:

  • APD warrants consideration as a neurodevelopmental disorder.
  • Future DSM revisions could include psychopathy as an APD specifier.
  • Early interventions targeting biological and health systems are recommended.