Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Predicting Reaction Outcomes02:24

Predicting Reaction Outcomes

11.0K
Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
11.0K
Outcomes of Glycolysis01:13

Outcomes of Glycolysis

107.8K
Nearly all the energy used by cells comes from the bonds that make up complex organic compounds. These organic compounds are broken down into simpler molecules, such as glucose. As a result, cells extract energy from glucose over many chemical reactions—a process called cellular respiration.
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
107.8K
Guidelines for Writing Outcome01:11

Guidelines for Writing Outcome

4.1K
When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
4.1K
Conservative Site-specific Recombination and Phase Variation02:53

Conservative Site-specific Recombination and Phase Variation

6.9K
Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
The recognition sites for Cre recombinase called LoxP...
6.9K
Specific Heat01:16

Specific Heat

67.8K
The specific heat capacity of a substance refers to the energy required to increase the temperature of one gram of that substance by one degree Celcius. Specific heat capacity is often represented in calories (cal), grams (g), and degrees Celsius (oC), but can also be expressed in joules (J), kilograms (kg), and Kelvin (K), among other units.
For example, increasing the temperature of one gram of water by 1°C requires one calorie of heat energy and can be written as 1 cal/g-°C, or...
67.8K
Density, Specific Weight, Specific Gravity and Compressibility of Fluid01:27

Density, Specific Weight, Specific Gravity and Compressibility of Fluid

1.7K
Density, specific weight, specific gravity, and compressibility are fundamental properties of fluids. Density is the mass per unit volume, characterizing the mass of a fluid system. It influences buoyancy, pressure, flow dynamics, viscosity, thermal conductivity, and sound propagation. For instance, in pipeline design, accurate density measurements ensure that the pipeline can handle the fluid's mass.
Specific weight represents the weight per unit volume and is calculated by multiplying...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluating the effectiveness of simvastatin in slowing the progression of disability in secondary progressive multiple sclerosis: a synopsis of MS-STAT2, a multicentre, randomised controlled, double-blind, phase 3 clinical trial.

Health technology assessment (Winchester, England)·2026
Same author

Use of UK national health databases for detecting intra-cranial aneurysm rupture in the Risk of Aneurysm Rupture (ROAR) study.

PLOS digital health·2026
Same author

Erythrocyte Fragility in Progressive Multiple Sclerosis.

European journal of neurology·2026
Same author

Estimating Rupture Risk of Intracranial Aneurysms: What We Know, What We Do Not Know, and What We Need.

Stroke·2026
Same author

Psychometric properties of the Chinese version of the Subarachnoid Hemorrhage Outcomes Tool (SAHOT) in elderly SAH patients.

BMC geriatrics·2026
Same author

Prospective patient-reported reasons for delayed diagnosis of spontaneous subarachnoid haemorrhage.

Emergency medicine journal : EMJ·2026

Related Experiment Video

Updated: Feb 15, 2026

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
10:34

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage

Published on: August 30, 2020

11.5K

A subarachnoid haemorrhage-specific outcome tool.

Adrian Pace1, Sophie Mitchell2, Elizabeth Casselden2

  • 1Greater Manchester Neurosciences Centre, Salford Royal NHS Foundation Trust, UK.

Brain : a Journal of Neurology
|February 6, 2018
PubMed
Summary

A new Subarachnoid Hemorrhage Outcome Tool (SAHOT) was developed and validated. This condition-specific measure accurately assesses functional outcomes, offering a robust alternative to general scales for subarachnoid hemorrhage patients.

More Related Videos

A Murine Model of Subarachnoid Hemorrhage
07:40

A Murine Model of Subarachnoid Hemorrhage

Published on: November 21, 2013

20.6K
A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage
08:12

A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage

Published on: July 28, 2018

8.5K

Related Experiment Videos

Last Updated: Feb 15, 2026

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
10:34

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage

Published on: August 30, 2020

11.5K
A Murine Model of Subarachnoid Hemorrhage
07:40

A Murine Model of Subarachnoid Hemorrhage

Published on: November 21, 2013

20.6K
A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage
08:12

A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage

Published on: July 28, 2018

8.5K

Area of Science:

  • Neuroscience
  • Clinical Assessment
  • Health Outcomes Research

Background:

  • Traditional functional outcome scales (e.g., modified Rankin Score, Glasgow Outcome Scale) have limitations when applied to subarachnoid hemorrhage (SAH).
  • A need exists for a condition-specific, scientifically validated tool to accurately measure SAH recovery.

Purpose of the Study:

  • To develop and validate a novel, condition-specific outcome tool for subarachnoid hemorrhage (SAHOT).
  • To assess the psychometric properties and clinical utility of the SAHOT.

Main Methods:

  • Item generation through focus groups with patients, caregivers, and healthcare professionals.
  • Iterative refinement and application of the SAHOT questionnaire at 1, 3, and 6 months post-SAH.
  • Rasch methodology for scale structure finalization and validation in a separate patient cohort.

Main Results:

  • The final 56-item SAHOT effectively measures cognitive, physical, and behavioral/psychological consequences of SAH.
  • Rasch analysis confirmed successful measurement of functional outcome with good validity, discrimination, and responsiveness.
  • The SAHOT demonstrated acceptability and was successfully validated in an independent patient cohort.

Conclusions:

  • The SAHOT is the first scientifically robust, SAH-specific outcome measure.
  • This tool offers significant potential for use in neurovascular clinical services and research.
  • SAHOT provides a more accurate assessment of functional recovery compared to generic scales.