Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Multiple Pipe Systems01:21

Multiple Pipe Systems

1.2K
Multipipe systems consist of complex configurations of interconnected pipes designed to transport fluids efficiently across intricate networks. They are essential in engineering applications requiring precise control over flow distribution, pressure, and head loss. They are categorized into series, parallel, loop, and network configurations, each distinguished by unique flow characteristics and applications.
Series Configuration
In a series configuration, fluid flows sequentially from one pipe...
1.2K
Bioavailability Study Design: Single Versus Multiple Dose Studies01:11

Bioavailability Study Design: Single Versus Multiple Dose Studies

253
Bioavailability studies are essential for understanding how a drug is absorbed, distributed, metabolized, and excreted in the body. These studies assess the extent and rate at which the active pharmaceutical agent becomes available at the site of action. The design of bioavailability studies can involve single-dose or multiple-dose regimens, each with distinct advantages and limitations.Single-dose studies are the preferred approach due to their simplicity and reduced drug exposure for...
253
Group Design02:01

Group Design

10.8K
The most basic experimental design involves two groups: the experimental group and the control group. The two groups are designed to be the same except for one difference— experimental manipulation. The experimental group gets the experimental manipulation—that is, the treatment or variable being tested—and the control group does not. Since experimental manipulation is the only difference between the experimental and control groups, we can be sure that any differences between...
10.8K
Heat and Free Expansion01:24

Heat and Free Expansion

3.0K
The work done by a thermodynamic system depends not only on the initial and final states but also on the intermediate states—that is, on the path. Like work, when heat is added to a thermodynamic system, it undergoes a change of state, and the state attained depends on the path from the initial state to the final state. Consider an ideal gas cylinder fitted with a piston. When the cylinder is heated at a constant temperature, the gas molecules absorb energy and expand slowly in a...
3.0K
Thermal Expansion01:22

Thermal Expansion

5.7K
The expansion of alcohol in a thermometer is one of many commonly encountered examples of thermal expansion, which is the change in size or volume of a given system as its temperature changes. The most visible example is the expansion of hot air. When air is heated, it expands and becomes less dense than the surrounding air, which then exerts an upward force on the hot air to, for example, make steam and smoke rise, and hot air balloons float. The same behavior happens in all liquids and gases,...
5.7K
Factorial Design02:01

Factorial Design

14.2K
Factorial Analysis is an experimental design that applies Analysis of Variance (ANOVA) statistical procedures to examine a change in a dependent variable due to more than one independent variable, also known as factors. Changes in worker productivity can be reasoned, for example, to be influenced by salary and other conditions, such as skill level. One way to test this hypothesis is by categorizing salary into three levels (low, moderate, and high) and skills sets into two levels (entry level...
14.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

pH-Triggered and Targeted Delivery of Curcumin: From Dendritic Polymers to Natural and Synthetic Nanocarriers.

Advanced healthcare materials·2025
Same author

Photophysical behavior of sulfur-oxidized sulfone and trifluoromethyl-BODIPY: Insight into the relationship between crystal structure and tumor cell imaging.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2025
Same author

A novel piperazine-linked BODIPY-pyrimidine anti-tumor fluorescent active drug: targeting mechanism, real-time dynamic imaging and delivery effect of DSPC/DPIC nanoparticles.

Bioorganic chemistry·2025
Same author

Multi-component driven fluorescence composite nanospheres coating strategy: Spectral properties, release, tumor imaging and bioactivity evaluation in a simulated gastrointestinal microenvironment.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2025
Same author

Based on sodium alginate coatings and dendritic copolymeric modification of curcumin delivery system: pH-sensitive nanospheres and strong tumor cytotoxicity.

International journal of biological macromolecules·2024
Same author

Correction: Efficacy and safety of teriparatide vs. bisphosphonates and denosumab vs. bisphosphonates in osteoporosis not previously treated with bisphosphonates: a systematic review and meta-analysis of randomized controlled trials.

Archives of osteoporosis·2024

Related Experiment Video

Updated: Feb 14, 2026

Super-resolution Imaging of Proteus mirabilis Biofilm by Expansion Microscopy
07:10

Super-resolution Imaging of Proteus mirabilis Biofilm by Expansion Microscopy

Published on: July 18, 2025

1.1K

Multiple surface expansion method for design of freeform imaging systems.

Ruirui Tang, Benqi Zhang, Guofan Jin

    Optics Express
    |February 7, 2018
    PubMed
    Summary

    This study introduces a novel freeform design method to enhance optical imaging systems. The method successfully achieves a large relative aperture size and a wide field-of-view (FOV) simultaneously.

    More Related Videos

    Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
    09:08

    Multiple-mouse Neuroanatomical Magnetic Resonance Imaging

    Published on: February 27, 2011

    16.5K
    Laser Micromachining for Polymer Surface Topography Design
    05:49

    Laser Micromachining for Polymer Surface Topography Design

    Published on: September 19, 2025

    512

    Related Experiment Videos

    Last Updated: Feb 14, 2026

    Super-resolution Imaging of Proteus mirabilis Biofilm by Expansion Microscopy
    07:10

    Super-resolution Imaging of Proteus mirabilis Biofilm by Expansion Microscopy

    Published on: July 18, 2025

    1.1K
    Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
    09:08

    Multiple-mouse Neuroanatomical Magnetic Resonance Imaging

    Published on: February 27, 2011

    16.5K
    Laser Micromachining for Polymer Surface Topography Design
    05:49

    Laser Micromachining for Polymer Surface Topography Design

    Published on: September 19, 2025

    512

    Area of Science:

    • Optical Engineering
    • Optical Design
    • Freeform Optics

    Background:

    • Simultaneously improving relative aperture size and field-of-view (FOV) in optical imaging systems presents a significant challenge.
    • Existing methods often face limitations in achieving high performance across both parameters.

    Purpose of the Study:

    • To propose and demonstrate a novel freeform design method for optical imaging systems.
    • To overcome the inherent trade-off between relative aperture size and FOV.
    • To design a high-performance freeform off-axis three-mirror imaging system.

    Main Methods:

    • A step-by-step freeform design approach is employed, progressively enlarging the FOV.
    • In each step, a portion of a system surface is constructed, optimizing performance.
    • The method is applied to design a freeform off-axis three-mirror imaging system.

    Main Results:

    • A freeform off-axis three-mirror imaging system was successfully designed.
    • The system achieved a large relative aperture size (F/2.5) and a wide FOV (60° × 1°).
    • The average root-mean-square wavefront error was 0.089λ at a working wavelength of 530.5 nm.

    Conclusions:

    • The proposed freeform design method is effective for high-performance optical imaging systems.
    • The method enables simultaneous optimization of relative aperture size and FOV.
    • This approach facilitates the development of advanced imaging systems with enhanced capabilities.