Varicella zoster virus-associated Chorioretinitis: a case report
Joo Yeon Kim1,2, Ji Hwan Lee3, Christopher Seungkyu Lee1
1Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Yonsei-ro 50-1, Seodaemun-gu, Seoul, South Korea.
BMC Ophthalmology
|February 7, 2018
Summary
Varicella zoster virus (VZV) can cause chorioretinitis, a rare form of posterior uveitis. Serial optical coherence tomography (OCT) documented the resolution of VZV-associated chorioretinitis after treatment.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Virology
Background:
- Chorioretinitis is an uncommon manifestation of varicella zoster virus (VZV)-associated uveitis.
- No prior reports have utilized serial optical coherence tomography (OCT) to illustrate the resolution process of VZV-associated chorioretinitis.
Observation:
- A 61-year-old female presented with acute, unilateral vision loss and forehead vesicles, indicative of VZV infection.
- Fundus examination revealed posterior pole inflammatory lesions, macular edema, and disc swelling in the affected eye.
- Optical coherence tomography (OCT) demonstrated primary involvement of the choroid and retinal pigment epithelium (RPE).
Findings:
- Intraocular fluid analysis confirmed the presence of VZV.
- Treatment with intravenous acyclovir and oral prednisolone led to the resolution of chorioretinal lesions within two weeks.
- Post-treatment OCT showed RPE undulation, and final visual acuity improved to 20/20.
Implications:
- Varicella zoster virus (VZV)-associated posterior uveitis can manifest as multifocal chorioretinitis.
- Intraocular fluid analysis is crucial for identifying infectious etiologies in posterior uveitis.
- Serial OCT imaging provides valuable insights into the resolution patterns of VZV-associated chorioretinitis.
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