Getting a kinematic handle on reach-to-grasp: a meta-analysis

Area of Science:

• Neuroscience
• Biomechanics
• Rehabilitation Science

Background:

• Reach-to-grasp is a fundamental daily activity.
• Stroke frequently impairs reach-to-grasp function.
• Understanding kinematic differences is crucial for effective rehabilitation.

Purpose of the Study:

• To identify kinematic differences in reach-to-grasp between stroke survivors and neurologically intact individuals.
• To determine the influence of object location on reach-to-grasp kinematics post-stroke.

Main Methods:

• Systematic review and meta-analysis following Cochrane Collaboration guidelines.
• Inclusion of studies with kinematic assessments of reach-to-grasp.
• Data synthesis using standardized mean difference (SMD) for kinematic characteristics.

Main Results:

• Twenty-nine studies involving 460 stroke survivors and 324 controls were analyzed.
• Significant kinematic differences were observed in central and ipsilateral workspaces.
• Stroke survivors exhibited lower peak velocity (SMD -1.48) and greater trunk displacement (SMD 1.55).
• Included studies had a high risk of bias.

Conclusions:

• Distinct kinematic patterns in reach-to-grasp exist between individuals with and without stroke.
• Object location may differentially affect kinematic characteristics.
• Findings are pertinent for optimizing reach-to-grasp retraining post-stroke.