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Updated: Feb 14, 2026

Primary Tumor and MEF Cell Isolation to Study Lung Metastasis
Published on: May 20, 2015
Orbital leiomyosarcoma metastasis presenting prior to diagnosis of the primary tumor
Nailyn Rasool1, Daniel R Lefebvre2, Mark A Latina2
1Edward Harkness Eye Institute, Columbia University, New York.
Abstract:
Leiomyosarcomas, neoplasms of smooth muscle, are rarely found within the orbit. Orbital leiomyosarcoma may be primary, metastatic, or secondary to radiation. When they are metastatic, patients almost exclusively have a history of a primary leiomyosarcoma, often occurring in the spermatic cord, skin, gastrointestinal tract, or the uterus. We present the case of 48-year-old woman who presented with a metastatic orbital leiomyosarcoma, which was identified before the primary tumor.
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