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Choroidal Thickness in Healthy Subjects.

Morteza Entezari1,2, Saeed Karimi1,3, Alireza Ramezani4

  • 1Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Journal of Ophthalmic & Vision Research
|February 7, 2018
PubMed
Summary

This study measured choroidal thickness using enhanced depth imaging optical coherence tomography (EDI-OCT) in normal Iranian eyes. Findings indicate choroidal thickness decreases with age but is comparable to other populations.

Keywords:
Enhanced Depth Imaging Optical Coherence TomographyHealthy SubjectsSubfoveal Choroidal thickness

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Anatomy

Background:

  • Choroidal thickness is a key parameter in ocular health.
  • Enhanced depth imaging optical coherence tomography (EDI-OCT) provides high-resolution imaging of the choroid.
  • Understanding normal choroidal thickness is crucial for diagnosing various eye conditions.

Purpose of the Study:

  • To measure choroidal thickness in normal Iranian eyes using EDI-OCT.
  • To establish normative data for choroidal thickness in this population.
  • To investigate the influence of age and sex on choroidal thickness.

Main Methods:

  • A prospective case series included 208 eyes from 104 healthy Iranian subjects.
  • Standard ophthalmic examinations were performed, with strict inclusion criteria.
  • Choroidal thickness was measured by EDI-OCT at subfoveal, 1500 μm, and 3000 μm locations (nasal and temporal to the fovea).

Main Results:

  • Mean subfoveal choroidal thickness was 363 ± 84 μm.
  • Thickness decreased with increasing distance from the fovea.
  • Choroidal thickness showed no significant difference between sexes but decreased significantly with age (P < 0.001).

Conclusions:

  • Mean choroidal thickness in normal Iranian subjects is comparable to international reports.
  • Age is a significant factor influencing choroidal thickness.
  • EDI-OCT is a valuable tool for assessing choroidal morphology.