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Related Experiment Videos

Early experience with the GIFT procedure.

S L Corson, F Batzer, E Eisenberg

    The Journal of Reproductive Medicine
    |April 1, 1986
    PubMed
    Summary

    Gamete intrafallopian transfer (GIFT) offers a viable infertility treatment for couples resistant to other methods. This procedure resulted in four conceptions, with three ongoing pregnancies.

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    Area of Science:

    • Reproductive Medicine
    • Infertility Treatment
    • Assisted Reproductive Technology

    Background:

    • Gamete intrafallopian transfer (GIFT) is an assisted reproductive technology.
    • It has been used for infertility cases resistant to conventional treatments.
    • Exclusion criteria included tubal disease.

    Purpose of the Study:

    • To evaluate the efficacy of Gamete intrafallopian transfer (GIFT) in couples with refractory infertility.
    • To assess indications including immunologic factors, seminal deficiencies, endometriosis, and unexplained infertility.

    Main Methods:

    • GIFT was performed in 19 cycles across 15 couples.
    • Stimulation protocols involved clomiphene citrate (CC) and human menopausal gonadotropins.
    • Sperm function was assessed using the hamster egg sperm penetration assay.

    Main Results:

    • Four conceptions were achieved from 19 GIFT cycles.
    • Three of the four pregnancies were ongoing at the time of reporting.
    • The study included both primary and secondary infertility cases.

    Conclusions:

    • GIFT is a potentially successful treatment for specific infertility cases.
    • Advantages include religious acceptance and physiological embryo transfer.
    • Potential disadvantages involve inability to confirm fertilization and risks of ectopic pregnancy or multiple gestations.

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