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Voltammetric quantitation of nitazoxanide by glassy carbon electrode
Rajeev Jain1, Rajeev Kumar Yadav1, Jahangir Ahmad Rather1
1School of Studies in Chemistry, Jiwaji University, Gwalior 474011, India.
Abstract:
The present study reports voltammetric reduction of nitazoxanide in Britton-Robinson (B-R) buffer by cyclic and square-wave voltammetry at glassy carbon electrode. A versatile fully validated voltammetric method for quantitative determination of nitazoxanide in pharmaceutical formulation has been proposed. A squrewave peak current was linear over the nitazoxanide concentration in the range of 20-140 µg/mL. The limit of detection (LOD) and limit of quantification (LOQ) was calculated to be 5.23 μg/mL and 17.45 μg/mL, respectively.
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