Related Experiment Video

Updated: Feb 14, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
05:26

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

Published on: May 28, 2019

9.7K

Reciprocal ST-Segment Changes in Myocardial Infarction: Ischemia at Distance Versus Mirror Reflection of ST-Elevation

Gaurang Nandkishor Vaidya1, Steve Antoine1, Syed Haider Imam2

  • 1Department of Medicine, SUNY Upstate Medical University, Syracuse, New York.

The American Journal of the Medical Sciences
|February 7, 2018
PubMed

Insights

Reciprocal ST-depression on ECGs in ST-elevation myocardial infarction (STEMI) does not predict collateral circulation. These ECG changes may indicate subendocardial ischemia or electrical phenomena, especially in patients presenting later.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Electrocardiography

Background:

  • Reciprocal ST-depression in ST-elevation myocardial infarction (STEMI) ECGs can stem from collateral circulation or electrical phenomena.
  • The predictive value of these reciprocal changes for collateral circulation remains unclear.

Purpose of the Study:

  • To determine if reciprocal ECG changes predict collateral circulation to the infarcted area in STEMI patients.
  • To differentiate between ischemic and electrical origins of reciprocal ST-depression.

Main Methods:

  • Retrospective review of ECG and coronary angiography data from 53 STEMI patients.
  • Independent expert analysis of ECG and angiography results, blinded to each other's findings.

Main Results:

  • Reciprocal changes (RC) were present in 77% of patients; collateral vessels were found in 26%.
  • No significant correlation was found between RC presence/depth and collateral circulation (P=0.384, P=0.195).
  • Resolution of RC after percutaneous coronary intervention (PCI) occurred in 84% of patients without collaterals (P=0.036). Patients without RC presented significantly later (P=0.004).

Conclusions:

  • Reciprocal changes on ECG lack predictive value for collateral circulation in STEMI.
  • RC were less frequent in patients presenting late, suggesting time-related resolution.
  • Reciprocal ST-depression likely represents subendocardial ischemia or an electrical phenomenon, not distant ischemia due to poor collateral flow.
Abstract

Keywords:
CardiacCatheterizationECGReciprocal changesSTEMI

More Related Videos

Induction of Myocardial Infarction and Myocardial Ischemia-Reperfusion Injury in Mice08:28

Induction of Myocardial Infarction and Myocardial Ischemia-Reperfusion Injury in Mice

Published on: January 19, 2022

8.4K
A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

24.8K

Related Concept Videos

Distance Problem01:29

Distance Problem

When an object's velocity changes over time, the total distance traveled can be determined by summing small displacement intervals over short increments. This approach approximates the true distance through numerical summation and the use of integral calculus. An estimate of the total displacement can be obtained by measuring velocity at regular intervals and multiplying each value by the corresponding time step.If a runner accelerates over the first three seconds of a race, speed measurements...
81
Freezing Point Depression and Boiling Point Elevation03:12

Freezing Point Depression and Boiling Point Elevation

Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
41.3K
The Sense of Self: Reflected Self-Appraisal and Social Comparison02:57

The Sense of Self: Reflected Self-Appraisal and Social Comparison

According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...
56.2K
The Distance Formula01:20

The Distance Formula

In geometry, measuring the direct distance between two points on a plane is essential in various practical and theoretical applications. Whether in navigation, engineering, or computer graphics, determining the shortest path between two locations involves using the distance formula. This formula is derived from the Pythagorean Theorem, which relates the lengths of the sides of a right triangle. On a coordinate plane, the horizontal and vertical distances between two points serve as the legs of...
662
Distance Corrections01:15

Distance Corrections

To achieve precise distance measurements, especially in surveying and construction, certain corrections must be applied to account for potential sources of error like the standardization errors, temperature variations, and slope adjustments.Standardization error emerges when measurement equipment undergoes changes, such as wear, repairs, or weather impacts. To address this, surveyors compare the equipment’s readings to a standard. This process identifies any deviation that might lead to...
303
Factors Influencing Attraction IV: Reciprocity01:28

Factors Influencing Attraction IV: Reciprocity

Reciprocity in attraction is fundamental to social and romantic relationships, shaping how individuals form and maintain connections. The psychological principle underlying this phenomenon is that people tend to like those who express liking toward them. Balance theory supports this tendency, suggesting that mutual attraction fosters psychological harmony, whereas one-sided affection leads to discomfort and cognitive dissonance.The Psychological Mechanisms Behind ReciprocityWhen individuals...
304