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Updated: Feb 14, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Prevention of Cardiovascular Disease
Brian V Reamy1, Pamela M Williams2, Daniel P Kuckel3
1F. Edward Hebert School of Medicine, Uniformed Services University, Office of the Senior Associate Dean for Academic and Faculty Affairs, 4301 Jones Bridge Road, Bethesda, MD 20814, USA.
Abstract:
Cardiovascular disease remains the leading cause of death in the United States and worldwide. Prevention of cardiovascular disease is an achievable goal. A rigorous 2010 analysis by the World Health Organization suggests that reducing risk factors in young adults and maintaining an optimum risk profile through age 50 could prevent 90% of atherosclerotic cardiovascular disease events. Misinformation and poor implementation of proven preventive strategies, misplaced fears of medications, or incorrect understanding of ideal dietary and lifestyle choices all contribute to poor risk profiles. Every patient deserves an individualized prescription for cardiovascular disease prevention incorporating strategies to control modifiable cardiovascular risk factors.
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