Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

3.7K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.7K
Gene Therapy00:59

Gene Therapy

27.7K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.7K
Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors01:20

Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors

1.3K
Antiplatelet drugs emerge as frontline defenders against the insidious threat of thromboembolic diseases, where abnormal clots obstruct vital blood vessels. These drugs stand as bulwarks, inhibiting platelet aggregation and clot formation, thereby mitigating the risk of life-threatening conditions like myocardial infarction, coronary artery disease, and thrombotic strokes.
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
1.3K
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

1.1K
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
1.1K
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

511
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
511
Group Therapy01:26

Group Therapy

472
Group therapy is a sociocultural approach to psychological treatment, where individuals with shared psychological challenges come together under the guidance of a mental health professional. This therapeutic modality offers unique opportunities for individuals to connect, share, and grow within the context of a supportive group. By fostering mutual understanding and collaboration, group therapy can address a range of psychological concerns effectively, often complementing or surpassing the...
472

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-World Safety Analysis of Paclitaxel Devices Used for the Treatment of Peripheral Artery Disease.

Journal of vascular and interventional radiology : JVIR·2023
Same author

Safety and efficacy of transcatheter edge-to-edge repair (TEER) in patients with history of cancer.

International journal of cardiology. Heart & vasculature·2023
Same author

Oral anticoagulation therapies among Medicare beneficiaries: Utilization and costs.

Vascular medicine (London, England)·2022
Same author

Active surveillance for implanted devices: strength in numbers.

BMJ surgery, interventions, & health technologies·2022
Same author

Impact of early surveillance on safety signal identification in the CathPCI DELTA study.

BMJ surgery, interventions, & health technologies·2022
Same author

Vascular Quality Initiative Surveillance of Femoropopliteal Artery Paclitaxel Devices.

JACC. Cardiovascular interventions·2021

Related Experiment Video

Updated: Feb 14, 2026

Regulatory T cells: Therapeutic Potential for Treating Transplant Rejection and Type I Diabetes
16:26

Regulatory T cells: Therapeutic Potential for Treating Transplant Rejection and Type I Diabetes

Published on: August 20, 2007

6.2K

Antiplatelet Therapy in Diabetes.

Arjun Majithia1, Deepak L Bhatt2

  • 1Division of Cardiovascular Medicine, Lahey Hospital and Medical Center, 41 Burlington Mall Road, Burlington, MA 01805, USA.

Endocrinology and Metabolism Clinics of North America
|February 7, 2018
PubMed
Summary

Patients with diabetes mellitus (DM) face higher risks of cardiovascular disease (CVD) due to increased platelet reactivity. Antiplatelet therapies are being investigated to prevent cardiovascular events in this population.

Keywords:
Antiplatelet therapyAntithrombotic therapyCardiovascular diseaseDiabetesThrombosis

More Related Videos

Transplantation of Pancreatic Islets Into the Kidney Capsule of Diabetic Mice
10:43

Transplantation of Pancreatic Islets Into the Kidney Capsule of Diabetic Mice

Published on: October 31, 2007

28.9K
Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells
11:13

Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells

Published on: April 7, 2016

9.6K

Related Experiment Videos

Last Updated: Feb 14, 2026

Regulatory T cells: Therapeutic Potential for Treating Transplant Rejection and Type I Diabetes
16:26

Regulatory T cells: Therapeutic Potential for Treating Transplant Rejection and Type I Diabetes

Published on: August 20, 2007

6.2K
Transplantation of Pancreatic Islets Into the Kidney Capsule of Diabetic Mice
10:43

Transplantation of Pancreatic Islets Into the Kidney Capsule of Diabetic Mice

Published on: October 31, 2007

28.9K
Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells
11:13

Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells

Published on: April 7, 2016

9.6K

Area of Science:

  • Cardiology
  • Endocrinology
  • Pharmacology

Background:

  • Diabetes mellitus (DM) is a major risk factor for cardiovascular disease (CVD).
  • Increased platelet reactivity in DM patients elevates atherothrombotic CVD risk.
  • Understanding antiplatelet therapy's role in DM is crucial for cardiovascular event prevention.

Purpose of the Study:

  • To investigate the role of antiplatelet therapies in patients with diabetes mellitus.
  • To explore the impact of these therapies on reducing cardiovascular events.

Main Methods:

  • Review of existing literature on antiplatelet agents and diabetes.
  • Analysis of clinical trial data concerning cardiovascular outcomes in diabetic patients treated with antiplatelet drugs.

Main Results:

  • Data suggests a significant association between enhanced platelet activity and CVD in diabetic individuals.
  • Exploration of antiplatelet therapies shows potential in mitigating atherothrombotic events.

Conclusions:

  • Antiplatelet therapies represent a promising strategy for managing cardiovascular risk in diabetes mellitus.
  • Further research is warranted to optimize antiplatelet treatment protocols for diabetic patients.