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Related Concept Videos

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The process of deriving the transfer function of a control system often involves reducing its block diagram to a single block. This simplification can be achieved through a series of strategic operations, including relocating branch points and comparators. These operations preserve the overall function of the system while allowing for easier manipulation and combination of blocks.
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Related Experiment Video

Updated: Feb 14, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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Persistent ventricular preexcitation despite right bundle branch block.

Taihei Itoh1, Takumi Yamada1

  • 1Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, AL, USA.

Indian Pacing and Electrophysiology Journal
|February 7, 2018
PubMed
Summary

This study identifies a rare fasciculo-ventricular pathway in a patient with supraventricular tachycardia. The pathway

Keywords:
Bundle branch blockFasciculoventricular pathwayMahaim fiberPreexcitation

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Area of Science:

  • Cardiology
  • Electrophysiology
  • Cardiac Anatomy

Background:

  • Ventricular preexcitation and supraventricular tachycardia are common arrhythmias.
  • Fasciculo-ventricular pathways are rare accessory pathways that can cause preexcitation.

Purpose of the Study:

  • To investigate the electrophysiological characteristics of a suspected fasciculo-ventricular pathway.
  • To determine the anatomical connection of the accessory pathway.

Main Methods:

  • Electrocardiogram (ECG) analysis during sinus rhythm and induced arrhythmias.
  • Pharmacological challenge with adenosine to assess pathway conduction properties.

Main Results:

  • Baseline ECG showed ventricular preexcitation with a normal PR interval and delta waves.
  • Adenosine administration revealed a fixed degree of preexcitation despite PR interval prolongation.
  • Complete right bundle branch block did not alter the degree of preexcitation.

Conclusions:

  • Findings suggest antegrade conduction over a fasciculo-ventricular pathway.
  • The pathway is likely connected to the left-sided His-Purkinje system.