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Related Concept Videos

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An acid-base reaction is one in which a hydrogen ion, H+, is transferred from one chemical species to another. Such reactions are of central importance to numerous natural and technological processes, ranging from the chemical transformations within cells or lakes and oceans to the industrial-scale production of fertilizers, pharmaceuticals, and other substances essential to the society.
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In 1923, G. N. Lewis proposed a generalized definition of acid-base behavior in which acids and bases are identified by their ability to accept or to donate a pair of electrons and form a coordinate covalent bond.
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This lesson delves into Lewis acids and bases in the context of the octet rule for electron-deficient compounds. Here, the concept is discussed, emphasizing the group 13 elements like boron or aluminium. Since group 13 elements possess three valence electrons, they form trivalent compounds with a sextet of electrons and a vacant orbital for the central atom. Consequently, these electron-deficient compounds accept electrons from other species to complete their octet in a chemical reaction. They...
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Salts with Acidic Ions
Salts are ionic compounds composed of cations and anions, either of which may be capable of undergoing an acid or base ionization reaction with water. Aqueous salt solutions, therefore, may be acidic, basic, or neutral, depending on the relative acid-base strengths of the salt’s constituent ions. For example, dissolving the ammonium chloride in water results in its dissociation, as described by the equation:
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The acid-base reaction class has been studied for quite some time. In 1680, Robert Boyle reported traits of acid solutions that included their ability to dissolve many substances, to change the colors of certain natural dyes, and to lose these traits after coming in contact with alkali (base) solutions. In the eighteenth century, it was recognized that acids have a sour taste, react with limestone to liberate a gaseous substance (now known to be CO2), and interact with alkalis to form neutral...
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A titration curve is a plot of some solution property versus the amount of added titrant. For acid-base titrations, solution pH is a useful property to monitor because it varies predictably with the solution composition and, therefore, may be used to monitor the titration’s progress and detect its endpoint. Acid-base titration can be performed with a strong acid and a strong base, a strong acid and a weak base, or a strong base and a weak acid.
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Fluorescence detection methods for microfluidic droplet platforms
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Microfluidic paper-based chip platform for benzoic acid detection in food.

Chan-Chiung Liu1, Yao-Nan Wang2, Lung-Ming Fu3

  • 1Department of Food Science, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.

Food Chemistry
|February 7, 2018
PubMed
Summary

A novel microfluidic paper-based analytical device (µPAD) integrated with a portable system enables accurate benzoic acid detection using the Janovsky reaction. This compact platform offers a reliable alternative to traditional methods for food sample analysis.

Keywords:
Benzoic acidMicrofluidicPaper-based assayPortable detection system

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Area of Science:

  • Analytical Chemistry
  • Microfluidics
  • Chemical Sensing

Background:

  • Benzoic acid is a common food preservative, necessitating reliable detection methods.
  • Existing analytical techniques can be complex and time-consuming.
  • Microfluidic paper-based analytical devices (µPADs) offer potential for portable and low-cost analysis.

Purpose of the Study:

  • To develop an integrated microfluidic platform for benzoic acid concentration detection.
  • To utilize the Janovsky reaction for colorimetric analysis of benzoic acid.
  • To create a portable and user-friendly system for food sample analysis.

Main Methods:

  • An integrated system combining a µPAD with a portable detection unit was designed.
  • Benzoic acid was derivatized to 3,5-Dinitrobenzoic acid and reacted on the µPAD.
  • Color changes were quantified using a CMOS camera and RGB analysis software on a smartphone.

Main Results:

  • The system demonstrated a strong correlation (R²=0.9953) between R(ed)+B(lue) intensity and benzoic acid concentration (500-4000 ppm).
  • Analysis of commercial food samples showed a maximum deviation of 6.6% compared to standard HPLC methods.
  • The developed platform proved effective for quantifying benzoic acid in real-world samples.

Conclusions:

  • The integrated microfluidic paper-based chip platform is a compact and reliable tool for benzoic acid measurement.
  • This approach offers a promising alternative for on-site food safety monitoring.
  • The system's accuracy and portability enhance its applicability in various settings.