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Updated: Feb 14, 2026

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Optimization of the metabolic stability of a fluorinated cannabinoid receptor subtype 2 (CB2) ligand designed for PET

Dominik Heimann1, Frederik Börgel1, Henk de Vries2

  • 1Institut für Pharmazeutische und Medizinische Chemie der Universität Münster, Corrensstraße 48, D-48149 Münster, Germany.

European Journal of Medicinal Chemistry
|February 7, 2018
PubMed

Keywords:
Amide bioisosteresCB(2) receptor ligandsFluorinated carbazole derivativesIdentification of metabolitesMetabolic stabilizationPETStructure affinity relationships

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