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New hydrazides derivatives of isoniazid against Mycobacterium tuberculosis: Higher potency and lower

Frederico Silva Castelo-Branco1, Evanoel Crizanto de Lima2, Jorge Luiz de Oliveira Domingos3

  • 1Fundacao Oswaldo Cruz, Instituto de Tecnologia em Fármacos, Farmanguinhos-Fiocruz, Departamento de Sintese Farmacos, Manguinhos, 21041-250 Rio de Janeiro, RJ, Brazil; Programa de Pos-Graduacao em Quimica da Universidade Federal do Rio de Janeiro, Instituto de Química, Departamento de Quimica Organica, 21941-909 Rio de Janeiro, RJ, Brazil.

European Journal of Medicinal Chemistry
|February 7, 2018
PubMed

Keywords:
ActivityCytotoxicityHepatotoxicityHydrazideIsoniazidTuberculosis

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