Related Experiment Video
Updated: Feb 14, 2026

Antibody Profiling by Luciferase Immunoprecipitation Systems LIPS
Published on: October 7, 2009
Spectrum of antibody profiles in tuberculous elephants, cervids, and cattle
Konstantin P Lyashchenko1, Christian Gortázar2, Michele A Miller3
1Chembio Diagnostic Systems, Inc., 3661 Horseblock Road, Medford, NY 11763, USA.
Abstract:
Using multi-antigen print immunoassay and DPP® VetTB Assay approved in the United States for testing captive cervids and elephants, we analyzed antibody recognition of MPB83 and CFP10/ESAT-6 antigens in Asian elephants (Elephas maximus) infected with Mycobacterium tuberculosis and in white-tailed deer (Odocoileus virginianus), fallow deer (Dama dama), elk (Cervus elaphus), and cattle (Bos taurus) infected with Mycobacterium bovis. Serum IgG reactivity to MPB83 was found in the vast majority of tuberculous cattle and cervid species among which white-tailed deer and elk also showed significant CFP10/ESAT-6 recognition rates with added serodiagnostic value. In contrast, the infected elephants developed antibody responses mainly to CFP10/ESAT-6 with MPB83 reactivity being relatively low. The findings demonstrate distinct patterns of predominant antigen recognition by different animal hosts in tuberculosis.
Related Concept Videos
The Electromagnetic Spectrum
The Electromagnetic Spectrum
IR Spectrum
Transmittance is defined as the ratio of the radiant power passing through a sample to that from the radiation's source. Multiplying the transmittance by 100 gives the percent transmittance (%T), which varies between 100% (no absorption) and 0%...
Mass Spectrum
UV–Vis Spectrum
The UV–Vis spectrum of a molecule is the plot of its absorbance versus wavelength. The plot is drawn by taking molar...
Mass Spectrum: Interpretation

