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Updated: Feb 14, 2026

Shape Memory Polymers for Active Cell Culture
Published on: July 4, 2011
Nanoimprinting of biomedical polymers reduces candidal physical adhesion
Hasanain Alalwan1, Christopher J Nile2, Ranjith Rajendran2
1Oral Sciences Research Group, School of Medicine, Dentistry and Nursing, College of Medical, Veterinary and Life Sciences; College of Dentistry, University of Baghdad, Iraq.
Abstract:
Management of fungal biofilms represents a significant challenge to healthcare. As a preventive approach, minimizing adhesion between indwelling medical devices and microorganisms would be an important step forward. This study investigated the anti-fouling capacity of engineered nanoscale topographies to the pathogenic yeast Candida albicans. Highly ordered arrays of nano-pit topographies were shown to significantly reduce the physical adherence capacity of C. albicans. This study shows a potential of nanoscale patterns to inhibit and prevent pathogenic biofilm formation on biomedical substrates.
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