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Updated: Feb 14, 2026

A Mouse Model of Lumbar Spine Instability
Published on: April 23, 2021
Biomechanical evaluation of exoskeleton use on loading of the lumbar spine
Eric B Weston1, Mina Alizadeh1, Gregory G Knapik1
1Spine Research Institute, The Ohio State University, Columbus, OH, United States; Department of Integrated Systems Engineering, The Ohio State University, Columbus, OH, United States.
Abstract:
The objective of this study was to investigate biomechanical loading to the low back as a result of wearing an exoskeletal intervention designed to assist in occupational work. Twelve subjects simulated the use of two powered hand tools with and without the use of a Steadicam vest with an articulation tool support arm in a laboratory environment. Dependent measures of peak and mean muscle forces in ten trunk muscles and peak and mean spinal loads were examined utilizing a dynamic electromyography-assisted spine model. The exoskeletal device increased both peak and mean muscle forces in the torso extensor muscles (p < 0.001). Peak and mean compressive spinal loads were also increased up to 52.5% and 56.8%, respectively, for the exoskeleton condition relative to the control condition (p < 0.001). The results of this study highlight the need to design exoskeletal interventions while anticipating how mechanical loads might be shifted or transferred with their use.
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