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Updated: Feb 14, 2026

An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
Published on: June 24, 2025
Intra-observer repeatability when assessing the foetal urinary bladder volume by the Virtual Organ Computer-aided
Mats A Fagerquist1,2, Vivek Sethi3, Eli Skytteren1
1Department of Obstetrics and Gynecology, Innlandet Hospital Trust, Kongsvinger Hospital, Norway.
Introduction:
The aim of this study was to compare the intra-observer repeatability when using two different methods for estimating the volume of foetal urinary bladders.
Method:
The urinary bladders of 20 foetuses were documented by three-dimensional ultrasound. Standard deviation was compared when the volumes of identical bladder images were repeatedly estimated using the Virtual Organ Computer-aided AnaLysis and the experimental SUM-OF-CYLINDERS methods.
Results:
No systematic deviation was found between the estimated volumes when using these two methods. Standard deviation was smaller for the SUM-OF-CYLINDERS compared to the Virtual Organ Computer-aided AnaLysis method (p < 0.0001). In relation to bladder volumes of 5-25 ml, standard deviation was 11-14% for the Virtual Organ Computer-aided AnaLysis and 4-5% for the SUM-OF-CYLINDERS method.
Conclusions:
Using three-dimensional ultrasound images adapted for the Virtual Organ Computer-aided AnaLysis method, foetal urinary bladder volumes can also be estimated using the SUM-OF-CYLINDERS method. The SUM-OF-CYLINDERS method employs technical advances which may result in a lower standard deviation and therefore higher intra-observer repeatability.
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