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Treatment patterns, costs, and mortality among Medicare beneficiaries with CIED infection
Arnold J Greenspon1, Elizabeth L Eby2, Allison A Petrilla3
1Cardiac Electrophysiology Laboratory, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Insights
Cardiac implantable electronic device (CIED) infections lead to high healthcare costs and mortality in Medicare beneficiaries. Preventing CIED infections is crucial to improve patient outcomes and reduce expenditures.
Area of Science:
- Cardiology
- Health Economics
- Infectious Diseases
Background:
- Cardiac implantable electronic device (CIED) infections are serious adverse events with limited real-world data on treatment and costs in Medicare.
- This study addresses the gap by evaluating treatment pathways, healthcare expenditures, and mortality following CIED infection in Medicare beneficiaries.
Purpose of the Study:
- To evaluate post-infection treatment pathways for CIED infections.
- To assess associated healthcare expenditures and mortality among Medicare fee-for-service beneficiaries.
- To identify cost drivers and inform prevention strategies.
Main Methods:
- Retrospective cohort analysis of 5,401 Medicare beneficiaries with CIED infection from 2010-2012.
- Patients were followed for 12 months post-infection diagnosis, categorized by device removal with or without replacement, or no intervention.
- Healthcare resource utilization and expenditures were measured.
Main Results:
- 64.1% of patients underwent device extraction; 39.0% had replacement, 25.1% without.
- Hospitalization was the primary cost driver, accounting for over 50% of expenditures for those with surgical intervention.
- Mean Medicare payments varied significantly by treatment group, with the highest for those hospitalized without device intervention ($77,397).
Conclusions:
- Management of CIED infections in Medicare beneficiaries incurs substantial healthcare expenditures within a year post-infection.
- High costs are driven by hospitalizations and surgical interventions like device extraction/replacement.
- Implementing additional preventive measures for CIED infections is essential to improve patient outcomes and reduce healthcare costs.
Background:
Cardiac implantable electronic device (CIED) infection is a serious adverse event, but there are limited contemporary real-world data on treatment pathways and associated costs in the Medicare population following diagnosis of CIED infection. Hence, this study evaluates postinfection treatment pathways and associated healthcare expenditures and mortality among Medicare fee-for-service beneficiaries with CIED infection.
Methods:
Retrospective cohort analysis of 5,401 beneficiaries who developed a device-related infection in the year following implantation/upgraded CIED (1/1/2010-12/31/2012). Patients were followed-up to 12 months/death following diagnosis of infection and were divided into mutually exclusive groups based on whether they underwent CIED system removal (Group I), or no CIED system intervention (Group II; IIA with or IIB without infection hospitalization). All-cause healthcare resource utilization/expenditures were also measured.
Results:
In the year following infection, 64.1% of patients underwent device extraction, of who 2,109 (39.0%) had their device replaced (Group IA) and 1,355 (25.1%) had their device extracted without replacement (Group IB); 62.2% of patients were hospitalized and 25.3% of patients died. Mean Medicare payments-per-patient for facility-based services by group were: IA = $62,638 (standard deviation [SD]: $46,830), IB = $50,079 (SD: $45,006), IIA = $77,397 (SD: $79,130), and IIB = $22,856 (SD: $31,167).
Conclusions:
Hospitalizations were the largest cost driver; infection-related costs, including cost of extraction/replacement, accounted for >50% of expenditures for patients with surgical/hospital intervention. Management of CIED infection in Medicare beneficiaries is associated with high healthcare expenditures in the year following infection. Additional measures to prevent device infection are needed to improve the outcomes and reduce costs in these patients.
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