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Updated: Feb 14, 2026

Functional and Morphological Assessment of Diaphragm Innervation by Phrenic Motor Neurons
Published on: May 25, 2015
Breathing: Motor Control of Diaphragm Muscle
Matthew J Fogarty1,2, Carlos B Mantilla1,3, Gary C Sieck1,3
1Department of Physiology and Biomedical Engineering, Mayo Clinic , Rochester, Minnesota.
Abstract:
Breathing occurs without thought but is controlled by a complex neural network with a final output of phrenic motor neurons activating diaphragm muscle fibers (i.e., motor units). This review considers diaphragm motor unit organization and how they are controlled during breathing as well as during expulsive behaviors.
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