Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Applications of Logarithms01:28

Applications of Logarithms

288
Logarithmic functions are powerful tools for simplifying the mathematical representation of phenomena involving exponential changes. Their ability to convert multiplicative relationships into additive ones is especially valuable in various scientific and engineering contexts. One notable application of logarithms is measuring sound intensity, specifically through the decibel (dB) scale used in acoustics.Sound intensity levels vary over an extensive range, from the faintest audible whisper to...
288
Environmental Applications of Microorganisms01:30

Environmental Applications of Microorganisms

1.2K
Microorganisms play a pivotal role in maintaining ecosystem balance by recycling essential elements such as carbon, nitrogen, and phosphorus, as well as supporting processes like bioremediation, wastewater treatment, and biofuel production.Microbes in Elemental CyclesIn the carbon cycle, microorganisms decompose organic matter, releasing carbon dioxide via aerobic respiration. This carbon dioxide is subsequently used by photosynthetic organisms to synthesize organic compounds, closing the...
1.2K
Photoluminescence: Applications01:14

Photoluminescence: Applications

1.1K
Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...
1.1K
Radiation: Applications01:17

Radiation: Applications

1.8K
The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
1.8K
Applications of Stress01:04

Applications of Stress

685
Consider a structure made of a boom and a rod designed to support a load. These two components are connected by a pin and stabilized by brackets and pins. The boom and the rod are detached from their supports to assess the different stresses imposed on this structure, and a free-body diagram is drawn. Then, all the forces applied, including the load acting on the structure, are identified. The reaction forces exerted on both the boom and the rod are computed using the equilibrium equations.
The...
685
Applications of Life Tables01:22

Applications of Life Tables

367
Life tables are versatile across various fields, providing a quantitative basis for analyzing mortality and survival rates. Whether used by demographers, actuaries, epidemiologists, or sociologists, life tables offer valuable insights into the dynamics of life and death, facilitating informed decisions in public health, insurance, conservation, and beyond. Their broad applicability highlights the interconnectedness of demographic data with practical outcomes in everyday life and strategic...
367

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outcome measures after anterior cervical decompression and fusion surgery -non-respondents do not bias the results: A Finnish spine register (FinSpine) study.

Brain & spine·2025
Same author

Author Correction: A dense ring of the trans-Neptunian object Quaoar outside its Roche limit.

Nature·2024
Same author

The feasibility of existing JADAS10 cut-off values in clinical practice: a study of data from The Finnish Rheumatology Quality Register.

Pediatric rheumatology online journal·2023
Same author

A dense ring of the trans-Neptunian object Quaoar outside its Roche limit.

Nature·2023
Same author

Neurocognition as a predictor of outcome in schizophrenia in the Northern Finland Birth Cohort 1966.

Schizophrenia research. Cognition·2018
Same author

Methods for Health Economic Evaluations of Vaccines - Results from an International Expert-Workshop.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2016
Same journal

From Music to Eczema: Dermatitis Caused by Para-Phenylenediamine in a Violinist.

Contact dermatitis·2026
Same journal

Reply to: Acrylate Copolymers/Crosspolymers in Sunscreens: Minimally Allergenic, Without Evidence of Need for Avoidance by (Meth)acrylate-Sensitized Individuals.

Contact dermatitis·2026
Same journal

Contact Allergy and Allergic Contact Dermatitis From Propylene Glycol and Related Glycols: Cosmetic Skin Sensitisers After All?

Contact dermatitis·2026
Same journal

Acrylate Copolymers/Crosspolymers in Sunscreens: Minimally Allergenic, Without Evidence of Need for Avoidance by (Meth)Acrylate-Sensitized Individuals.

Contact dermatitis·2026
Same journal

AI-Assisted Automated Two-Stage Patch Test Interpretation System Using Vision Transformer.

Contact dermatitis·2026
Same journal

Use of Tralokinumab in a Hairdresser With Severe Chronic Hand Eczema and Occupational Allergic Contact Dermatitis.

Contact dermatitis·2026
See all related articles

Related Experiment Video

Updated: Feb 12, 2026

Repeated Orotracheal Intubation in Mice
06:26

Repeated Orotracheal Intubation in Mice

Published on: March 27, 2020

19.6K

The repeated open application test (ROAT).

M Hannuksela, H Salo

    Contact Dermatitis
    |April 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Repeated open application tests (ROATs) can improve diagnosis of allergic contact dermatitis. ROATs are particularly useful for identifying reactions to common vehicle ingredients when patch tests are inconclusive.

    More Related Videos

    Modification and Application of a Leaf Blower-vac for Field Sampling of Arthropods
    09:43

    Modification and Application of a Leaf Blower-vac for Field Sampling of Arthropods

    Published on: August 10, 2016

    9.2K
    A Novel Application of Musculoskeletal Ultrasound Imaging
    10:53

    A Novel Application of Musculoskeletal Ultrasound Imaging

    Published on: September 17, 2013

    24.7K

    Related Experiment Videos

    Last Updated: Feb 12, 2026

    Repeated Orotracheal Intubation in Mice
    06:26

    Repeated Orotracheal Intubation in Mice

    Published on: March 27, 2020

    19.6K
    Modification and Application of a Leaf Blower-vac for Field Sampling of Arthropods
    09:43

    Modification and Application of a Leaf Blower-vac for Field Sampling of Arthropods

    Published on: August 10, 2016

    9.2K
    A Novel Application of Musculoskeletal Ultrasound Imaging
    10:53

    A Novel Application of Musculoskeletal Ultrasound Imaging

    Published on: September 17, 2013

    24.7K

    Area of Science:

    • Dermatology
    • Allergology
    • Contact Dermatitis Research

    Background:

    • Contact dermatitis is a common skin condition often triggered by allergens in topical products.
    • Standard patch testing may not always accurately identify causative agents, especially for vehicle ingredients.
    • Repeated open application tests (ROATs) offer an alternative diagnostic method.

    Purpose of the Study:

    • To evaluate the efficacy of ROATs in diagnosing allergic contact dermatitis.
    • To compare ROAT results with standard patch test results for common vehicle ingredients.
    • To assess the utility of ROATs in cases with suspected unknown or new allergens.

    Main Methods:

    • Conducted ROATs on 86 patients with contact dermatitis using common vehicle ingredients.
    • Applied substances twice daily for 7 days to the forearm, monitoring for dermatitis.
    • Compared ROAT outcomes with initial patch test results, including specific analysis for propylene glycol.

    Main Results:

    • 44% of patients with questionable patch test results showed positive reactions in ROATs.
    • 80% of patients with positive patch tests reacted positively in ROATs (excluding propylene glycol).
    • ROATs identified reactions to lower concentrations of propylene glycol in cream formulations.

    Conclusions:

    • ROATs are a valuable tool for diagnosing allergic contact dermatitis, especially when patch tests are equivocal.
    • The study supports increased use of ROATs for suspected allergies to vehicle ingredients.
    • ROATs demonstrate higher sensitivity for certain allergens like propylene glycol in relevant concentrations.