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Updated: Feb 14, 2026

A Murine Model of Vertical Sleeve Gastrectomy
Published on: December 18, 2017
Technical innovation: Intragastric Single Port Sleeve Gastrectomy (IGSG). A feasibility survival study on porcine
Oscar Estupinam1, André Lacerda de Abreu Oliveira2, Fernanda Antunes3
1MSc in Sciences, Animal Experimentation Division, Laboratory of Animal Health, Center for Agricultural Sciences and Technologies, Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Campos dos Goytacazes-RJ, Brazil. Conception and design of the study, technical procedures, acquisition and analysis of data, manuscript writing.
Purpose:
To perform technically the laparoscopic sleeve gastrectomy (LSG) using a unique Intragastric Single Port (IGSG) in animal swine model, evidencing an effective and safe procedure, optimizing the conventional technique.
Methods:
IGSG was performed in 4 minipigs, using a percutaneous intragastric single port located in the pre-pyloric region. The gastric stapling of the greater curvature started from the pre-pyloric region towards the angle of His by Endo GIA™ system and the specimen was removed through the single port. In the postoperative day 30, the animals were sacrificed and submitted to autopsy.
Results:
All procedures were performed without conversion, and all survived 30 days. The mean operative time was 42 min. During the perioperative period no complications were observed during invagination and stapling. No postoperative complications occurred. Post-mortem examination showed no leaks or infectious complications.
Conclusion:
Intragastric Single Port is a feasible procedure that may be a suitable alternative technique of sleeve gastrectomy for the treatment of morbid obesity.
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