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Delirium in the Elderly.

Tammy T Hshieh1, Sharon K Inouye2, Esther S Oh3

  • 1Division of Aging, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 1620 Tremont Street, One Brigham Circle, 3rd Floor, Boston, MA 02120, USA.

The Psychiatric Clinics of North America
|February 8, 2018
PubMed
Summary
This summary is machine-generated.

Delirium, an acute disturbance in attention and cognition, significantly impacts patient morbidity and mortality. This review covers its epidemiology, diagnosis, pathophysiology, and advances in nonpharmacological prevention and treatment.

Keywords:
Cognitive declineDeliriumDelirium preventionDementiaNonpharmacological interventions

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Area of Science:

  • Geriatrics
  • Critical Care Medicine
  • Neuroscience

Background:

  • Delirium is an acute confusional state characterized by disturbances in attention and cognition.
  • It is associated with increased morbidity, mortality, and prolonged hospital stays.
  • Understanding its epidemiology and pathophysiology is crucial for effective management.

Purpose of the Study:

  • To provide a comprehensive overview of delirium.
  • To discuss current approaches to diagnosis, assessment, and workup.
  • To highlight recent advances in prevention and treatment strategies.

Main Methods:

  • Literature review of epidemiology, pathophysiology, diagnosis, and treatment of delirium.
  • Focus on multicomponent, nonpharmacological interventions.
  • Discussion of predisposing and precipitating factors.

Main Results:

  • Delirium presents with acute changes in attention and cognition.
  • Various factors contribute to its development, including patient-specific vulnerabilities and acute stressors.
  • Nonpharmacological interventions show promise in prevention and treatment.

Conclusions:

  • Effective management of delirium requires a thorough understanding of its multifaceted nature.
  • Early diagnosis and prompt intervention are key to improving patient outcomes.
  • Multicomponent, nonpharmacological strategies represent a significant advancement in delirium care.