Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Plasticity00:58

Plasticity

3.1K
Plasticity is the property where an object loses its elasticity and undergoes irreversible deformation, even after the deformation forces are eliminated. If a material deforms irreversibly without increasing stress or load, then this is called ideal plasticity. For example, when a force is applied to an aluminum rod, it changes its shape, but it does not return to its original shape once the force is removed. Plastic deformation or ductility is thus a permanent deformation or change in the...
3.1K
Plasticizers01:31

Plasticizers

379
Water-reducers, or plasticizers, are chemical admixtures used in concrete to improve strength and workability. These additives reduce the water-cement ratio without compromising workability, lower the cement content while maintaining the same workability, or increase workability to assist concrete placement in inaccessible areas.
Plasticizers function by using surface-active agents to create repulsive electrostatic forces between cement particles. This dispersion enhances the concrete's...
379
Plastic Behavior01:21

Plastic Behavior

598
A material's elastic behavior is characterized by the disappearance of stress once the load is removed, allowing the material to return to its original state. However, when stress surpasses the yield point, yielding commences, marking the onset of plastic deformation or permanent set. This change from elastic to plastic behavior is influenced by the peak stress value and the duration before the load is removed. An intriguing observation occurs when a specimen is loaded, unloaded, and...
598
Plastic Deformations01:14

Plastic Deformations

485
It is essential to understand how structural members behave under plastic deformation when the bending stress exceeds the material's yield strength. This state of deformation permanently alters the shape of the member, in contrast to the linear elastic behavior observed before yielding. The strain at any point in the member is expressed in terms of maximum strain. Notably, the neutral axis, which coincides with the centroid during elastic bending, shifts away from the centroid under plastic...
485
Plastic Deformations01:19

Plastic Deformations

480
Plastic deformation represents a fundamental concept in materials science, which explains the irreversible change in the shape of a material when it experiences stress beyond its elastic capability. This phenomenon is important in structural engineering, especially in designing and analyzing cantilever beams—structures that are securely fixed at one end and bear loads at the opposite end. When these beams are subjected to loads within their elastic range, they will return to their...
480
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

1.4K
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Amyloid Beta Oligomers as Early Triggers of Neuronal Cytoskeleton Dysfunction in Alzheimer's Disease.

Pathophysiology : the official journal of the International Society for Pathophysiology·2026
Same author

RETRACTED: Jarero-Basulto et al. Cytotoxic Effect of Amyloid-β1-42 Oligomers on Endoplasmic Reticulum and Golgi Apparatus Arrangement in SH-SY5Y Neuroblastoma Cells. <i>NeuroSci</i> 2024, <i>5</i>, 141-157.

NeuroSci·2025
Same author

RETRACTED: Cytotoxic Effect of Amyloid-β1-42 Oligomers on Endoplasmic Reticulum and Golgi Apparatus Arrangement in SH-SY5Y Neuroblastoma Cells.

NeuroSci·2024
Same author

Correction: Viveros-Paredes et al. Neuroprotective Effects of β-Caryophyllene against Dopaminergic Neuron Injury in a Murine Model of Parkinson's Disease Induced by MPTP. <i>Pharmaceuticals</i> 2017, <i>10</i>, 60.

Pharmaceuticals (Basel, Switzerland)·2024
Same author

Bee Venom Reduces Early Inflammation and Oxidative Stress Associated with Lipopolysaccharide-induced Alpha-synuclein in the Substantia Nigra-striatum Axis.

Cell biochemistry and biophysics·2024
Same author

Early expression of monomeric and oligomeric alpha-synuclein and reduction of tyrosine hydroxylase following intranigral injection of lipopolysaccharide.

Molecular biology reports·2024

Related Experiment Video

Updated: Feb 14, 2026

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring
11:28

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring

Published on: June 13, 2025

1.4K

Interactions Between Epilepsy and Plasticity.

José J Jarero-Basulto1, Yadira Gasca-Martínez2, Martha C Rivera-Cervantes3

  • 1Cellular Neurobiology Laboratory, Cell and Molecular Biology Department, CUCBA, University of Guadalajara, 45220 Zapopan, Jalisco, Mexico. jose.jarero@academicos.udg.mx.

Pharmaceuticals (Basel, Switzerland)
|February 8, 2018
PubMed
Summary

Neuroplasticity allows the brain to adapt to stimuli like epilepsy. This review explores how seizure-induced changes in the hippocampus may lead to temporal lobe epilepsy.

Keywords:
epilepsygranular cellshippocampusplasticityseizures

More Related Videos

A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery
09:41

A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery

Published on: May 20, 2016

12.8K
Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
09:32

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

13.0K

Related Experiment Videos

Last Updated: Feb 14, 2026

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring
11:28

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring

Published on: June 13, 2025

1.4K
A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery
09:41

A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery

Published on: May 20, 2016

12.8K
Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
09:32

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

13.0K

Area of Science:

  • Neuroscience
  • Neurobiology

Background:

  • The central nervous system exhibits neuroplasticity, modifying structure and function in response to stimuli.
  • Neuroplasticity can be induced by environmental factors, internal state changes, and pathological conditions like epilepsy.
  • Epilepsy and neuroplasticity are closely intertwined, potentially influencing each other.

Purpose of the Study:

  • To analyze neuroplastic changes in the hippocampus following seizure-induced neuronal damage.
  • To investigate the role of these neuroplastic changes in the development of temporal lobe epilepsy.

Main Methods:

  • Literature review of studies on neuroplasticity and epilepsy.
  • Analysis of neuroplastic alterations in the hippocampus post-seizure.
  • Examination of mechanisms linking neuronal damage to epilepsy establishment.

Main Results:

  • Seizure-induced neuronal damage triggers specific neuroplastic changes in the hippocampus.
  • These hippocampal neuroplastic alterations are implicated in the progression to temporal lobe epilepsy.
  • The relationship between epilepsy and neuroplasticity is bidirectional and complex.

Conclusions:

  • Neuroplasticity plays a critical role in the pathophysiology of temporal lobe epilepsy.
  • Understanding these mechanisms can inform future therapeutic strategies for epilepsy.
  • Further research is needed to fully elucidate the interplay between neuroplasticity and seizure disorders.