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Updated: Feb 17, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
[Thrombectomy in secondary and/or late thrombosis of branches of the aortic bifurcation prosthesis]
Insights
Aortic bifurcation prostheses showed a 5.5% thrombosis rate, influenced by surgical techniques, patient factors, and anticoagulation. Thrombectomy outcomes were compared to other bypass procedures.
Area of Science:
- Vascular Surgery
- Biomaterials Science
- Clinical Outcomes Research
Background:
- Atherosclerotic lesions commonly affect the aortic bifurcation, necessitating reconstructive surgery.
- Prosthetic grafts are frequently used for aorto-bi-femoral or aorto-bi-iliac reconstruction, excluding aneurysms.
Purpose of the Study:
- To analyze the incidence and causes of thrombosis in aortic bifurcation prostheses.
- To compare the efficacy of thrombectomy versus alternative reconstructive procedures for thrombosed grafts.
Main Methods:
- Retrospective analysis of 1,100 aortic bifurcation prostheses (aorto-bi-femoral/iliac) implanted between 1974-1984.
- Evaluation of thrombosis development, prosthesis material (primarily double velvet Dacron), operative techniques, distal arterial bed status, and anticoagulant therapy.
- Comparison of thrombectomy outcomes with other bypass surgeries for similar indications.
Main Results:
- Global thrombosis development rate was 5.5% across all prostheses.
- Potential contributing factors to thrombosis included surgical techniques, distal arterial conditions, and anticoagulation status.
- Outcomes of thrombectomy were evaluated against alternative reconstructive methods.
Conclusions:
- Thrombosis remains a significant complication following aortic bifurcation prostheses implantation.
- Surgical technique, patient-specific arterial factors, and anticoagulation management are critical considerations.
- Thrombectomy presents a viable option, with outcomes comparable to other reconstructive approaches in specific scenarios.
Abstract:
Between 1974 and 1984, 1,100 prostheses of the aortic bifurcation, aorto-bi-femoral or aorto-bi-iliac, were inserted for atherosclerotic lesions: aneurysms were excluded from this analysis. The most frequently used prosthesis material was of double velvet Dacron. Global percent thrombosis development was 5.5%. Possible causes of the thrombosis are the operative techniques, the distal arterial bed and the presence or absence of associated anticoagulant therapy. Techniques used and results obtained with thrombectomy on one or more thrombosed prosthesis branches are compared with other reconstructive procedures for similar indications, particularly atypical axillo-femoral or inter-femoral by-pass operations. Results of this comparison may appear surprising but are nevertheless perfectly logical.
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