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Induced Sputum as a Diagnostic Tool in Pneumonia in Under Five Children-A Hospital-based Study

Aditya Kurade1, Sara Dhanawade1, Sachin Shetti2

  • 1Department of Pediatrics, Bharati Vidyapeeth Deemed University Medical College and Hospital, Sangli, Maharashtra 416416, India.

Journal of Tropical Pediatrics
|February 8, 2018
PubMed

Insights

Sputum induction in children under five is safe and feasible, yielding a high rate of bacterial identification. Success rates varied by age, with older children showing better results.

Area of Science:

  • Pediatric Pulmonology
  • Infectious Diseases
  • Microbiology

Background:

  • Pneumonia is a leading cause of mortality in children under five.
  • Accurate microbiological diagnosis is crucial for effective pneumonia treatment.
  • Sputum induction is a potential diagnostic tool for lower respiratory tract infections in young children.

Purpose of the Study:

  • To evaluate the success and tolerability of sputum induction in children younger than five years.
  • To identify bacterial isolates from induced sputum in this age group.

Main Methods:

  • A cross-sectional study involving 120 hospitalized children aged 1-59 months with WHO-defined pneumonia.
  • Sputum induction was performed using 3% hypertonic saline.

Main Results:

  • Overall sputum induction success was 53.3%, highest in the 37-59 months age group (64.28%).
  • Adverse events included tachypnea (41.6%), hypoxemia (17.5%), and vomiting (15.8%).
  • A pathogen was isolated in 70.3% of cases with good quality sputum, with Klebsiella pneumoniae being the most common.

Conclusions:

  • Sputum induction is a safe and feasible procedure for young children in Indian settings.
  • Despite limited overall success, sputum induction provides a high bacterial yield for diagnosing pneumonia in children.
Abstract

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