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Related Experiment Video

Updated: Feb 14, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
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One-year outcomes after rapid-deployment aortic valve replacement.

Christopher Young1, Günther Laufer2, Alfred Kocher2

  • 1St Thomas' Hospital, Cardiac Surgery Department, London, United Kingdom.

The Journal of Thoracic and Cardiovascular Surgery
|February 9, 2018
PubMed
Summary

Rapid-deployment aortic valve replacement using the EDWARDS INTUITY valve system shows excellent short-term safety and performance. This minimally invasive approach reduces aortic crossclamp time, improving patient outcomes in a broad European setting.

Keywords:
aortic valve replacementbioprosthesisheart valvehemodynamics

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Area of Science:

  • Cardiovascular Surgery
  • Medical Devices
  • Prosthetic Heart Valves

Background:

  • Rapid-deployment aortic valve replacement aims to minimize invasiveness and reduce aortic crossclamp duration.
  • The EDWARDS INTUITY valve system is designed for faster implantation during aortic valve procedures.

Purpose of the Study:

  • To evaluate the short-term safety and performance of the EDWARDS INTUITY valve system.
  • To assess procedural outcomes, hemodynamic performance, and adverse events in a European multicenter study.

Main Methods:

  • A prospective, multicenter European registry (26 centers) enrolled 517 patients.
  • 493 patients received the EDWARDS INTUITY valve system, with technical success assessed.
  • Follow-up extended up to 2 years, evaluating hemodynamic function and clinical outcomes.

Main Results:

  • Technical success rate was 95.4% with a mean follow-up of 1.8 years.
  • Significant improvements in effective orifice area and reductions in pressure gradients were observed.
  • One-year freedom from death was 93.5%, with low rates of major bleeding and perivalvular leak.

Conclusions:

  • The EDWARDS INTUITY valve system demonstrates commendable short-term safety and performance.
  • The findings support its use in a broad European patient population undergoing aortic valve replacement.