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Burkitt's lymphoma with placental invasion diagnosed at cesarean delivery: a case report
Cielo Gnecco1, S J Carlan2, Jeannie McWhorter1
1Department of Obstetrics and Gynecology, Orlando Regional Healthcare, Orlando, FL, USA.
Background:
Burkitt's lymphoma is a highly aggressive B cell non-Hodgkin lymphoma subtype. Its occurrence in pregnancy is rare and often results in a delayed diagnosis. The treatment plan and prognosis depend on a number of variables including the stage at diagnosis.
Case Presentation:
A 32 weeks pregnant, 34-year-old white woman presented with weeks of complaints that were similar to typical pregnancy symptoms. Laboratory and ultrasound findings suggested a pathologic process and during the workup non-reassuring fetal surveillance resulted in an emergency cesarean delivery. Biopsies were obtained that confirmed Burkitt's lymphoma. Placental histology revealed microscopic involvement.
Conclusions:
The placenta should be inspected for microscopic disease if Burkitt's lymphoma is suspected, even if a vaginal delivery occurs and the placenta is ordinarily discarded. Repetitive somatic complaints during pregnancy should not be assumed to be secondary to the normal symptoms of pregnancy.