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[Systemic sclerosis: Efficacy of intravenous immunoglobulins in severe cardiac involvement?]

C Cacciatore¹, S Riviere¹, A Cohen²

¹Service de médecine interne and inflammation (DHU i2B), université Paris 06, hôpital Saint-Antoine, AP-HP, 75012 Paris, France.

La Revue De Medecine Interne

|February 9, 2018

Abstract

Background:

The heart involvement in systemic sclerosis is frequent and can touch various sites. The prognosis in the presence of heart disease is poor, but few data are available about its management.

Case:

We report the case of 48 years old woman with systemic sclerosis which presented severe heart involvement. She has severe heart failure, supraventricular arrhythmias and symptomatic pericarditis, which required surgical intervention and immunosuppressive drugs (steroids with rituximab). Despite this treatment, she has persistent severe heart impaired function and intravenous immunoglobulins have been initiated. She experienced progressively the improvement of dyspnea, of heart systolic ejection fraction and decrease of Rodnan scale.

Conclusion:

Our case illustrates a severe heart involvement in systemic sclerosis which have been improved by intravenous immunoglobulins.

Keywords:

Atteinte cardiaque Heart involvement Immunoglobulines intraveineuses Intravenous immunoglobulins Sclérodermie systémique Systemic sclerosis

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