Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brainstem01:19

Brainstem

6.7K
The brainstem, located inferior to the brain and superior to the spinal cord, serves as a bridge between the cerebrum and the spinal cord. It plays a vital role in relaying information and controlling critical life functions. It comprises three primary regions: the midbrain, pons, and medulla oblongata.
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
6.7K
Resonance02:52

Resonance

66.6K
The Lewis structure of a nitrite anion (NO2−) may actually be drawn in two different ways, distinguished by the locations of the N-O and N=O bonds.
66.6K
The Auditory Ossicles01:11

The Auditory Ossicles

3.2K
The auditory ossicles of the middle ear transmit sounds from the air as vibrations to the fluid-filled cochlea. The auditory ossicles consist of two malleus (hammer) bones, two incus (anvil) bones, and two stapes (stirrups), one on each side. These bones develop during the fetal stage and are the ones to ossify first. They are fully mature at birth and do not grow afterward.
The aptly named stapes look very much like a stirrup. The three ossicles are unique to mammals, and each plays a role in...
3.2K
Auditory Perception01:17

Auditory Perception

1.2K
The auditory system is essential for sound perception, utilizing various critical structures. When sound waves enter the outer ear, they travel through the ear canal and cause the eardrum to vibrate. These vibrations are then transmitted to the middle ear, where three tiny bones – the malleus, incus, and stapes – amplify the sound. This amplification is crucial, as it ensures that the sound vibrations are strong enough to be conveyed to the inner ear. These vibrations then reach the...
1.2K
Auditory Pathway01:15

Auditory Pathway

7.5K
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
7.5K
Brainstem: Control Centers of Medulla01:21

Brainstem: Control Centers of Medulla

4.4K
The medulla oblongata is a crucial part of the brainstem responsible for controlling various autonomic and involuntary functions. It contains several nuclei, including the olivary, cuneate, gracile, and solitary nuclei.
Olivary Nucleus
The olivary nucleus, or inferior olivary nucleus, is located within the ventrolateral part of the medulla oblongata. It is primarily involved in motor coordination and motor learning. The olivary nucleus receives input from the spinal cord, cerebellum, and motor...
4.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A vast temporal continuum for sensory processing arises from a nontopographic cellular multilevel gradient.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Non-calyceal inputs gate the timing of calyx of Held evoked MNTB output.

Communications biology·2026
Same author

Comparison of place field detection methods and their effect on place field stability and drift in mouse dCA1.

Journal of neuroscience methods·2026
Same author

Impact of Sinbaglustat on Neurons of the Medial Nucleus of the Trapezoid Body in a Murine Model of Human G<sub>M1</sub>-Gangliosidosis.

Journal of clinical medicine·2026
Same author

Formation of task representations and replay in mouse medial prefrontal cortex.

eLife·2026
Same author

A population approach to cortical GABAergic interneuron function.

Neuron·2026

Related Experiment Video

Updated: Feb 14, 2026

In Ovo Electroporation in the Chicken Auditory Brainstem
10:14

In Ovo Electroporation in the Chicken Auditory Brainstem

Published on: June 9, 2017

9.0K

Resonance Properties in Auditory Brainstem Neurons.

Linda Fischer1, Christian Leibold2,3, Felix Felmy1

  • 1Zoologisches Institut, Stiftung Tierärztliche Hochschule Hannover, Hannover, Germany.

Frontiers in Cellular Neuroscience
|February 9, 2018
PubMed
Summary

Auditory brainstem neurons use membrane potential resonances, driven by potassium currents, to process sound frequencies. Tuning membrane time constants offers a flexible way to adjust this frequency tuning.

Keywords:
LSOMSOVNLLauditory brainstemmembrane resonance

More Related Videos

Preparation and Culture of Chicken Auditory Brainstem Slices
11:16

Preparation and Culture of Chicken Auditory Brainstem Slices

Published on: March 21, 2011

11.5K
Slicing the Embryonic Chicken Auditory Brainstem to Evaluate Tonotopic Gradients and Microcircuits
08:24

Slicing the Embryonic Chicken Auditory Brainstem to Evaluate Tonotopic Gradients and Microcircuits

Published on: July 12, 2022

2.5K

Related Experiment Videos

Last Updated: Feb 14, 2026

In Ovo Electroporation in the Chicken Auditory Brainstem
10:14

In Ovo Electroporation in the Chicken Auditory Brainstem

Published on: June 9, 2017

9.0K
Preparation and Culture of Chicken Auditory Brainstem Slices
11:16

Preparation and Culture of Chicken Auditory Brainstem Slices

Published on: March 21, 2011

11.5K
Slicing the Embryonic Chicken Auditory Brainstem to Evaluate Tonotopic Gradients and Microcircuits
08:24

Slicing the Embryonic Chicken Auditory Brainstem to Evaluate Tonotopic Gradients and Microcircuits

Published on: July 12, 2022

2.5K

Area of Science:

  • Neuroscience
  • Auditory Processing
  • Computational Neuroscience

Background:

  • Auditory signals contain information across diverse timescales.
  • Auditory brainstem nuclei are specialized for frequency-specific information extraction.
  • Membrane potential resonances are a biophysical mechanism for frequency selectivity.

Purpose of the Study:

  • Investigate subthreshold membrane resonances in auditory brainstem nuclei.
  • Determine the biophysical basis and determinants of these resonances.
  • Assess the role of resonance tuning in frequency-specific auditory processing.

Main Methods:

  • Electrophysiological recordings from three auditory brainstem nuclei.
  • Analysis of subthreshold membrane potential dynamics.
  • Linear modeling of resonance properties and their dependence on membrane time constant.

Main Results:

  • Observed high-frequency subthreshold membrane resonances in all studied nuclei.
  • Identified low-threshold potassium currents as the likely basis for these resonances.
  • Demonstrated that the steady-state membrane time constant is the primary determinant of resonance frequency.

Conclusions:

  • Subthreshold membrane resonances are a common feature in the auditory brainstem.
  • Tuning the membrane time constant via leak conductance provides a flexible mechanism for frequency-specific signal processing.
  • These findings offer insights into the neural basis of auditory frequency perception.