Related Experiment Video
Updated: Feb 14, 2026

Multifractal Spectrum Analysis for Assessing Pulmonary Nodule Malignancy
Published on: January 10, 2025
Advanced Imaging Techniques in Skull Base Osteomyelitis Due to Malignant Otitis Externa
A M J L van Kroonenburgh1, W L van der Meer1, R J P Bothof2
11Department of Radiology, Maastricht University Medical Center, P. Debyelaan 25, 6229 HX Maastricht, The Netherlands.
Diagnosing skull base osteomyelitis (SBO) requires combining anatomical and functional imaging. PET-MRI and high-resolution CT (HRCT) offer complementary strengths for accurate SBO assessment.
Area of Science:
- Radiology
- Nuclear Medicine
- Infectious Diseases
Background:
- Skull base osteomyelitis (SBO) is a challenging infection.
- Accurate diagnosis and monitoring are crucial for effective treatment.
- Current imaging techniques have limitations in fully characterizing SBO.
Purpose of the Study:
- To provide a comprehensive review of current imaging modalities for SBO.
- To evaluate the strengths and weaknesses of each technique.
- To guide optimal imaging strategies for SBO diagnosis and follow-up.
Main Methods:
- Review of computed tomography (CT) and magnetic resonance imaging (MRI) for anatomical detail.
- Assessment of nuclear medicine techniques for functional imaging of infection.
- Evaluation of hybrid imaging modalities like PET-CT and PET-MRI.
Main Results:
- CT and MRI provide essential anatomical information.
- Nuclear techniques are valuable for assessing disease activity.
- Hybrid PET-CT and PET-MRI integrate anatomical and functional imaging capabilities.
Conclusions:
- No single imaging modality is sufficient for comprehensive SBO evaluation.
- A combined approach utilizing both anatomical and functional imaging is recommended.
- For suspected SBO, PET-MRI (including T1, T2, T1-FS-GADO, DWI sequences) and HRCT are suggested for diagnosis and follow-up.
More Related Videos
Related Concept Videos
Sample Preparation for Analysis: Advanced Techniques
Acid digestion with strong acids is commonly used to dissolve inorganic materials that are insoluble (do not dissolve) in water. This method can be useful for...
Sutures of the Skull
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques
Overview of the Skull
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
Overview of Advanced Functional Groups
Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
Types of Advanced Functional Groups
The table below summarizes some of the major functional groups in organic chemistry.
Extraction: Advanced Methods

