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P50 Sensory Gating in Infants
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Fulminant hepatitis E in an infant.

Drishti Tolani1, Ira Shah1

  • 1Department of Pediatrics, Pediatric Liver Clinic, B J Wadia Hospital for Children, Mumbai, Maharashtra, India.

Journal of Family Medicine and Primary Care
|February 9, 2018
PubMed
Summary
This summary is machine-generated.

Fulminant hepatitis E, a severe liver condition, can occur in children. This case highlights that Hepatitis E virus (HEV) infection in a one-year-old can be successfully managed with supportive care due to its self-limiting nature.

Keywords:
Fulminant hepatitishepatitis Einfant

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Area of Science:

  • Hepatology
  • Virology
  • Pediatrics

Background:

  • Hepatitis E virus (HEV) is a significant cause of acute liver inflammation, primarily spread through contaminated water.
  • While often self-limiting, HEV infection poses a higher risk for severe outcomes, particularly fulminant hepatic failure, in pregnant women.
  • HEV is endemic in developing countries, presenting in both sporadic and epidemic forms.

Observation:

  • A rare case of fulminant hepatitis E was observed in a one-year-old child.
  • The child presented with severe symptoms including jaundice, hepatic encephalopathy, and coagulopathy.
  • This presentation is unusual as HEV infection is typically subclinical in young children.

Findings:

  • The child's condition was managed with symptomatic treatment.
  • Recovery was attributed to the inherent self-limiting course of Hepatitis E virus infection.
  • Prompt supportive care played a crucial role in the patient's outcome.

Implications:

  • This case underscores that fulminant hepatitis E, though rare, can occur in young children.
  • It emphasizes the importance of prompt symptomatic management for severe HEV cases in pediatric populations.
  • Further research into HEV's varied clinical spectrum in children is warranted.