Duchenne muscular dystrophy: Case report and review

Area of Science:

• Neurology
• Genetics
• Pediatrics

Background:

• Muscular dystrophies encompass diverse disorders marked by progressive muscle weakness.
• Duchenne muscular dystrophy (DMD) is the most prevalent X-linked muscular dystrophy in children, typically diagnosed in early childhood.
• DMD presents with proximal muscle weakness, calf hypertrophy, delayed motor development, and potential cardiac/respiratory complications.

Observation:

• This report details a case of DMD in a 12-year-old male patient.
• The case exhibits notable clinical and oral manifestations associated with the disorder.
• Current treatments like corticosteroids and ventilation offer symptomatic relief but not a cure.

Findings:

• The case underscores the varied clinical spectrum of Duchenne muscular dystrophy.
• Specific attention is given to the oral health aspects in pediatric DMD patients.
• The study emphasizes the importance of comprehensive patient evaluation.

Implications:

• Understanding DMD's clinical heterogeneity is crucial for effective management.
• Further research into novel therapies is essential for a potential cure.
• This case contributes to the knowledge base for managing pediatric DMD, including oral health considerations.